無症候性原発性胆汁性肝硬変の1例

概要

論文の詳細を見る
A 65 ycar-old female was suspected as chronic hepatitis and received therapy a few years ago. On admission no particular symptom was fbund. Pruritus and jaundice were not observed.<BR>Laboratory examination showed as fbllows: Total cholesterol 260 mg/dl; total bilirubin 0.5mg/dl; γ-globulin 2.39/dl; IgG 2960 mgldl; IgM 540 mg/dl; ICG (retention rate after 15 min.)7%; HBs antigen(-); HBs an tibody(+); GOT 49 U; GPT 21 U; γ-GTP 120.0μU/ml; LAP 856 U; Al-Pase 28.9 K.A. U.; RA-test(+); serum copper 205 μg/dl; anti-nuclear antibody(+); antimitochondrial antibody(+); anti-smooth muscle antibody (+). Liver scintigram showed no particular findings. The endoscopic retrograde cholangiography revealed no biliary obstruction. No varix was found on gastro-camera examination in the stomach and esophagus. Surgical liver wedge biopsy specimen showed so called chronic nonsuppurative destructive cholangitis, described by Rubin<BR>From these results the case was corresponding to asymptomatic primary biliary cirrhosis reported by Fox et al.
社団法人日本肝臓学会の論文