Epidemiologic Risk Factors of Cleft Lip and/or Palate in Japan
スポンサーリンク
概要
- 論文の詳細を見る
This paper described a case-control study on cleft lip and/or palate which aimed to disclose demographic and epidemiologic risk factors. Cases in this study were defined as the infants born with cleft lip and/or palate during the study period from April, 1978 to September, 1981, who visited two specified hospitals and lived in one of five cities. Controls were randomly selected from normal infants who were born in a major hospital in each city during the study period. Controls were matched to cases, with an allocation ratio of 1 : 1, for sex, birth order, residential area, and maternal age at birth to within one year. Routine demographic and numerous epidemiologic information were collected by direct interview of the study subjects mothers at home by one interviewer. Routine statistical analysis by odds ratio with 95% confidence interval was carried out on 194 cases, who comprized 55 cases with cleft lip alone, 87 with cleft lip and palate, and 52 with cleft palate alone, in comparison with 194 matched controls. Major findings are as follows: 1) A significantly elevated risk was associated with parental lower educational attainment, parental occupation of unskilled/ service workers, previous episode of artificial abortion, family history of cleft lip and/or palate, and maternal smoking habits at the first trimester, and maternal episodes at the first trimester of suffering from any diseases (common cold in particular), and of ingesting any drugs (cold remedies in particular). 2) A significantly reduced risk was linked with frequent maternal consumption at the first trimester of such animal proteins as meats, fishes and shells, eggs and milk. 3) Maternal episodes of spontaneous abortion/stillbirth, radiation exposure and frequent maternal consumption at the first trimester of fresh vegetables, fruits, Japanese tea, and black tea were not significantly associated. 4) Frequent maternal consumption of coffee at the first trimester significantly elevated the risk, but turned to be insignificant after statistical adjustment of maternal smoking habits. Causal implications were discussed on these epidemiologic factors which significantly enhanced or reduced the risk.Cleft lip and/or palate, Case-control study, Risk factors, Epidemiology, Japan
著者
-
Tohnai Iwai
Department Of Oral And Maxillofacial Surgery Nagoya University Graduate School Of Medicine
-
Ohno Yoshiyuki
Department Of Pharmacy Kinjogakuin University
-
Kaneda Toshiro
Department of Oral Surgery, Nagoya University School of Medicine
関連論文
- 帯状疱疹により歯の自然脱落と歯槽骨壊死をきたした2例
- 透視下に除去した下顎管内異物の1例
- 舌癌に対する浅側頭動脈よりの超選択的動注法を用いた放射線化学療法 : 多施設共同研究の取り組みについて
- 浅側頭動脈よりの超選択的動注法(HFT法)を用いた連日同時放射線化学療法 : 進行口腔癌の原発温存に対する検討
- 下顎歯肉癌に対する浅側頭動脈と後頭動脈よりの超選択的動注法 : 顎動脈と顔面動脈へのカテーテル同時留置術
- 口腔癌に対する超選択的動注化学療法のための後頭動脈よりのカテーテル留置術
- 下顎エナメル上皮腫の治療における超音波骨メスの使用経験
- 咀嚼筋隙に生じた静脈奇形に対する内視鏡を併用したナビゲーション支援手術
- 口腔組織の再生医療 : 顎骨再生の臨床研究と血管, 神経の再生について
- 口腔癌再建術後, 肘正中皮静脈から挿入した中心静脈カテーテルにより生じた右腕頭静脈血栓症の1例
- 下歯槽神経が歯根を貫通していた下顎第3大臼歯の1例
- 側頭筋に生じた血管腫の1例
- 経過観察中に下顎骨下縁より突出した逆性過剰埋伏歯の1例
- 遊離腓骨皮弁による下顎再建術後に生じた下肢深部静脈血栓症の1例
- 下顎骨関節突起頸部骨折に対する内視鏡を用いた観血的整復固定術の1例
- 上顎洞底挙上術における超音波骨メスの使用経験
- 前歯部歯槽骨切り術の臨床統計的検討
- 抗リン脂質抗体症候群を合併した顎変形症患者の全身麻酔経験
- 歯槽膿瘍に対する炭酸ガスレーザー照射後に生じた顔面・頸部・縦隔気腫の1例
- 上顎洞内迷入歯摘出術に対するナビゲーションシステムの使用経験
- TS-1^【○!R】長期内服中患者に発生したガス産生性頬部蜂巣炎の1例
- Lung Cancer Mortality and Serum Levels of Carotenoids, Retinol, Tocopherols, and Folic Acid in Men and Women : a Case-Control Study Nested in the JACC Study
- Updated Information on Risk Factors for Lung Cancer : Findings from the JACC Study
- Epidemiologic and Clinical Characteristics of Cardiomyopathies in Japan : Results From Nationwide Surveys
- Dietary Habits and Risk of Lung Cancer Death in a Large-scale Cohort Study (JACC Study) in Japan by Sex and Smoking Habit
- Decrease in Risk of Lung Cancer Death in Males after Smoking Cessation by Age at Quitting : Findings from the JACC Study
- Tea Consumption and Lung Cancer Risk : A Case-Control Study in Okinawa, Japan
- Serum carotenoids and mortality from lung cancer : a case-control study nested in the Japan Collaborative Cohort (JACC) Study
- The Relationship between Smoking Habits and Serum Levels of 8-OHdG, Oxidized LDL Antibodies, Mn-SOD and Carotenoids in Rural Japanese Residents
- Depressive Mood and Suicide Among Middle-Aged Workers : Findings from a Prospective Cohort Study in Nagoya, Japan
- Estimated Number of Patients with Chronic Renal Failure but not with End-Stage Renal Disease in Japan : Comparisons Between Two Estimation Methods
- 高IgE症候群患者の抜歯に対する周術期管理の1例
- Validity and Reliability of Single-item Questions about Physical Activity
- Estimated Prevalence and Incidence of Adult Still's Disease : Findings by a Nationwide Epidemiological Survey in Japan
- Case-Control Study of Oral Cancer in Shenyang, Northeastern China
- 浅側頭動脈よりの超選択的動注法による術前連日同時放射線化学療法が著効した口底粘表皮癌の1例
- Similar and Dissimilar Findings in Japan-Indonesia Case-Control Study on Breast Cancer : Two Phases Study
- A case-control study on risk factors for scleroderma
- Selective hyperthermia using magnetoliposomes to target cervical lymph node metastasis in a rabbit tongue tumor model
- Suicide gene therapy using adenovirus vector for human oral squamous carcinoma cell line In vitro
- Life-Style Related Factors and Idiopathic Dilated Cardiomyopathy : A Case-Control Study Using Pooled Controls
- Nutritional factors and risk of pancreatic cancer : a population-based case-control study based on direct interview in Japan
- Cigarette Smoking as a Risk Factor for Chronic Pancreatitis : A Case-Control Study in Japan
- Nationwide epidemiological survey of chronic pancreatitis in Japan
- Comparison of Accelerometry and Oxymetry for Measuring Daily Physical Activity
- Smoking, Alcohol, Sleep and Risk of Idiopathic Sudden Deafness : A Case-Control Study Using Pooled Controls
- Sleep Patterns and Total Mortality : A 12-Year Follow-up Study in Japan
- EPIDEMIOLOGICAL EVALUATION OF FUNDUSCOPIC FINDINGS IN CEREBROVASCULAR DISEASES : III. OBSERVER VARIABILITY AND REPRODUCIBILITY FOR FUNDUSCOPIC FINDINGS : Original Articles written in English
- 舌口腔底再建における工夫
- Primary Clinical Effects of PP Therapy (Cisplatin and Peplomycin) and TPP Therapy (4^1-O-tetrahydropyranyladriamycin, Cisplatin and Peplomycin) for Oral Cancer
- Intracellular Localization and Partial Amino Acid Sequence of a Stress-Inducible 40-kDa Protein in HeLa Cells
- Up-regulation of CD109 expression is associated with carcinogenesis of the squamous epithelium of the oral cavity
- Association of Major Histocompatibility Complex Class I Chain-Related Gene A and HLA-B Alleles with Behcet's Disease in Turkey
- 進行口腔癌に対する浅側頭動脈よりの超選択的動注法を用いた連日同時放射線化学療法 : 腫瘍栄養動脈による頸部転移リンパ節への病理組織効果
- 口腔癌に対する docetaxel, cisplatin を用いた浅側頭動脈よりの超選択的動注化学療法と放射線療法との術前連日同時併用療法の有害事象に関する検討
- 内視鏡支援下に完全口内法で整復固定した関節突起基底部骨折の1例
- 血管造影撮影(DSA)による外頸動脈とその分枝の検討
- 内視鏡支援下に下顎骨嚢胞性病変を摘出した1例
- ビスフォスフォネート投与により生じた下顎骨壊死の1例
- 口腔癌に対するCDDP・5-FU併用化学療法後に発症したSIADHの1例
- Evaluation of Maxillary Sinus Floor Augmentation Using Mixture of Autogenous Bone and Highly Pure Porous β-tricalcium Phosphate (β-TCP) : A Preliminary Study
- Cell Death of Human Oral Squamous Cell Carcinoma Cell Line Induced by Herpes Simplex Virus Thymidine Kinase Gene and Ganciclovir
- Effect of the Combination of a Local OK-432 Injection and Hyperthermia on SCC VII Tumors in Mice
- Gene mutation analysis and immunohistochemical study of β-catenin in odontogenic tumors
- ORAL INJURY AND THE USE OF MOUTH GUARDS - SOCCER, RUGBY, BASKETBALL PLAYER IN JAPANESE HIGH SCHOOL-
- Cotranslocation and Colocalization of hsp40 (DnaJ) with hsp70 (DnaK) in Mammalian Cells
- Epidemiologic Risk Factors of Cleft Lip and/or Palate in Japan
- Epidemiological Approaches to Identify Risk Factors for Human Congenital Malformations : Descriptive and Analytical Epidemiology of Cleft Lip and/or Palate in Japan
- Efficacy of Tooth Extraction Wound Protection Made of Atelocollagen Sponge (TRE-641) : A Pilot Study in Dogs
- Combination with allogenic bone reduces early absorption of β-tricalcium phosphate (β-TCP) and enhances the role as a bone regeneration scaffold. Experimental animal study in rat mandibular bone defects
- Apatite Deposition on Several Dental Biodegradable Materials in Simulated Body Fluid
- Chemotherapy using Intra-Arterial Infusion for Oral Cancer
- 超音波プローブ誘導性能向上のための一手法 : 術中超音波画像と磁気式カテーテルナビゲーションの融合
- 口腔癌に対するカテーテルナビゲーション応用を想定した異なる環境下における磁気式位置精度の検討
- Primary sebaceous carcinoma of the tongue
- The Clinical and Histopathological Effects of Combined Chemotherapy Using Cisplatin and Peplomycin to Treat Cancer of the Tongue
- Leiomyosarcoma of the Maxillary Gingiva : A Case Report
- Assessment of tumor hypoxia by ^Cu-ATSM PET/CT as a predictor of response in head and neck cancer : a pilot study
- 温熱療法を併用した逆行性超選択的動注化学放射線療法が著効した上顎歯肉癌N3の1例
- 口腔がん治療に関する私感
- 超進行癌の治療はどこまでするか : 逆行性超選択的動注化学療法を中心に
- 進行口腔癌に対する逆行性超選択的動注化学療法, 放射線同時併用療法後の救済手術
- TS-1による化学療法と温熱放射線療法が著効した後発頸部リンパ節転移の1例
- 新しい接着性顎間固定用アーチバーの臨床的応用
- 下顎第三大臼歯抜去4週間後に生じた下顎骨骨折の1例
- Anatomical study of the external carotid artery and its branches for administration of superselective intra-arterial chemotherapy via the superficial temporal artery
- 両側浅側頭動脈よりの超選択的動注法を用いた連日同時放射線化学療法を施行した舌背部扁平上皮癌の1例
- 癌化学療法における口内炎に対するG-CSF(グラン^【○!R】)含嗽製剤の有用性に関する検討 : Preliminary study
- 第3回国際口腔腫瘍学会 (3^ World Congress of the International Academy of Oral Oncology : IAOO) に出席して
- 進行口腔癌に対する逆行性超選択的動注化学放射線療法
- 下顎の深部埋伏大臼歯に対して頬側皮質骨骨切り術を用いて抜歯した2例
- 眼窩頬骨骨折治療後に残遺した顔面非対称に対しナビゲーション支援手術を施行した1例
- 吸収性ミニプレートを用いて内視鏡支援下に整復固定した下顎骨関節突起基底部骨折の1例
- エコーガイド下に口内法で摘出した耳下腺導管内唾石の1例
- 頸部郭清術標本中に偶然発見された甲状腺乳頭癌リンパ節転移の1例
- 両側上下顎に生じた臼後歯の1例
- 口底癌(T4aN3M0)に対して温熱化学放射線療法が著効した1例
- オトガイ形成術の2時間後に気道閉塞を併発した1症例
- 下顎智歯周囲炎を契機に発見された組織球性壊死性リンパ節炎の1例
- Thermochemoradiotherapy for Oral Cancer with N2, 3 Cervical Lymph Node Metastases using Retrograde Superselective Intra-arterial Infusion