pm大腸癌の臨床像

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During the 15 years from January 1965 to December, 1980, Twenty four cases with colonrectal cancer in which cancer extension was limited to the muscular layer (pm) were experienced among 269 cases of resected colorectal cancer at the First Department of Surgery, Nagasak iUniversity Hospital, and evaluated in clinicopathological aspects.<BR>1) Most of the onset syndromes were bloody stool and/or melena. The initial sym-ptoms of bloody stool have been thought to be an important clue of early detection as far as the tumors were situated in the lower colon. 2) The size of pm cancer was within 5 cm, most were less than 3 cm and the tumors usually occupied two third or half of the cross-sectional circumference of the gut wall and were mostly ulcerative-localized type on gross appearance.<BR>3) From the aspect of hisiologic type, pm-colorectal cancers were well and/or moderately differentiated carcinoma. Lymph node involvement were not frequent (7%). As far as the involved lymph nodes were concerned, in pm-colorectal cancer these were confined to the regional lymph node (n1).<BR>4) Histologically, vascular invasion was more frequently than would be sxpected. observed. The vascular and lymphatic invasions in surgical specimens were histologically exarmined. Their incidence was 37% and 67% respectively. Liver metastasis and peritoneal dissemination, however, were not experienced among the 24 cases. In conclusion, curative operation is feasible in the pm-colorectal cancer and it is necessary to enhance the cure rate with an more early opeation in spite of pm-colorectal cancer.
日本大腸肛門病学会の論文

pm大腸癌の臨床像

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