A Case of Mixed Medullary and Follicular Cell Carcinoma of the Thyroid
スポンサーリンク
概要
- 論文の詳細を見る
A medullary thyroid carcinoma is a malignant tumor derived from the C-cells of the thyroid. Despite their distinct embryological origin, medullary thyroid carcinomas are exceptionally accompanied by a tumor derived from the follicular cells; this is defined as mixed medullary and follicular cell carcinoma. There have been controversies regarding the origin of this rare mixed thyroid carcinoma questioning whether or not a mixed carcinoma originates from a common cancer stem cell. We present a case of mixed medullary and follicular cell carcinoma in which two thyroid carcinomas were found intermingled in the thyroid as well as in the metastatic cervical lymph nodes. We examined the tumor by immunostaining with thyroglobulin, calcitonin, and thyroid transcription factor-1, and also reviewed the literature and discuss the origin of this rare mixed thyroid carcinoma.
著者
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Imaizumi Misa
Department Of Clinical Studies (nagasaki) Radiation Effects Research Foundation
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Kawakami Atsushi
Department Of Biological Information Tokyo Institute Of Technology
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Ando Takao
Department Of Cardiology Nihon University School Of Medicine
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Hayashi Tomayoshi
Department Of Cardiovascular Surgery And Pathology Nagasaki University School Of Medicine
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Uga Tatsuya
Department Of Surgery Nagasaki University Graduate School Of Biomedical Sciences
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Ueki Ikuko
Department Of Endocrinology And Metabolism Unit Of Translational Medicine Graduate School Of Biomedi
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Horie Ichiro
Department Of Endocrinology And Metabolism Unit Of Translational Medicine Graduate School Of Biomedi
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Usa Toshiro
Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Haraguchi Ai
Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Hayashi Tomayoshi
Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Ando Takao
Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Horie Ichiro
Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Ueki Ikuko
Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Uga Tatsuya
Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Imaizumi Misa
Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Japan
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Kawakami Atsushi
Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, Japan
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