HomotraurineとHexamethoniumの諸種交感神経節における節遮断作用について

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1. Homotaurine (HT) and hexamethonium (C6) showed remarkable inhibitory effects on the pressor responses following electrical stimulations of the splanchnic nerves in dogs. 2. HT and C6 showed remarkable inhibitory effects on the rise of inferior mesenteric arterial perfusion pressure following preganglionic stimulation (P. S.) of the inferior mesenteric ganglion (I. M. G.), but no effects on the rise of perfusion pressure by post ganglionic stimulation, in dogs. 3. The contractile force of the nictitating membrane following P. S. of the superior cervical ganglion was not inhibited by HT, but inhibited by C6, in dogs. 4. In cats, the ganglionic potential following P. S. of I. M. G. was not inhibited by HT, but inhibited remarkably by C6. In Dogs, the postganglionic action potential following P. S. of I. M. G. was inhibited remarkably by HT.
社団法人日本薬理学会の論文