Pseuduvarines A and B, Two New Cytotoxic Dioxoaporphine Alkaloids from Pseuduvaria rugosa
スポンサーリンク
概要
- 論文の詳細を見る
Pseuduvarines A (1) and B (2), two new dioxoaporphine alkaloids with an amino moiety, were isolated from the stem bark of Pseuduvaria rugosa and their structures were elucidated by combination of 2D-NMR spectroscopic analysis. Pseuduvarines A (1) and B (2) showed cytotoxicity against MCF7, HepG2, and HL-60 (1: IC50, 0.9, 21.7, and >50.0 μM, respectively, 2: IC50 >50.0, 15.7, and 12.4 μM, respectively).
著者
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Hadi A.
Department of Chemistry, Faculty of Science, University of Malaya
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Morita Hiroshi
Faculty Of Environment Engineering The University Of Kitakyushu
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Kaneda Toshio
Faculty of Pharmaceutical Sciences, Hoshi University
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Mohamad Khalit
Department of Pharmacy, Faculty of Medicine, University Malaya
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Shirota Osamu
Faculty of Pharmaceutical Sciemces at Kagawa Campus, Tokushima Bunri Universiyty
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Nugroho Alfarius
Faculty of Pharmaceutical Science, Hoshi University
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Taha Hairin
Department of Chemistry, Faculty of Science, University of Malaya
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Nordin Noraziah
Department of Chemistry, Faculty of Science, University of Malaya
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Najmuldeen Ibrahim
Department of Chemistry, Faculty of Science, University of Malaya
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Piow Wong
Faculty of Pharmaceutical Sciences, Hoshi University
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