Oppositinines A and B: New Vasorelaxant β-Carboline Alkaloids from Neisosperma oppositifolia
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概要
- 論文の詳細を見る
A phytochemical study on the bark of Neisosperma oppositifolia (Apocynaceae) yielded two new β-carboline indole alkaloids, oppositinines A (1) and B (2), together with five known alkaloids, isoreserpiline, isocarapanaubine, vobasine, 10-methoxydihydrocorynantheol-N-oxide, and ochropposinine oxindole. Structural elucidation of 1 and 2 was performed using 2D NMR methods. Oppositinines A (1) and B (2) showed potent vasorelaxant effects on the rat aorta.
著者
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Ahmad Kartini
Department of Chemistry, Faculty of Science and Technology, University Pendidikan Sultan Idris
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Thomas Noel
Department of Chemistry, Faculty of Science, University of Malaya
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Hadi A.
Department of Chemistry, Faculty of Science, University of Malaya
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Mukhtar Mat
Department of Chemistry, Faculty of Science, University of Malaya
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Mohamad Khalit
Department of Pharmacy, Faculty of Medicine, University of Malaya
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Nafiah Mohd
Department of Chemistry, Faculty of Science and Technology, University Pendidikan Sultan Idris
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Takeya Koichi
Tokyo University of Pharmacy and Life Sciences
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Morita Hiroshi
Faculty of Pharmaceutical Sciences, Hoshi University
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Litaudon Marc
Institut de Chimie des Substances Naturelles
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Arai Hiroko
Faculty of Pharmaceutical Sciences, Hoshi University
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Awang Khalijah
Department of Chemistry, Faculty of Science, University of Malaya
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Takeya Koichi
Tokyo College Of Pharmacy
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Awang Khalijah
Department Of Chemistry University Of Malaya
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Hadi A.
Dep. Of Chemistry Fac. Of Sci. Univ. Of Malaya
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Morita Hiroshi
Faculty Of Pharmaceutical Sciences Hoshi University:laboratory Of Pharmacotherapeutics Showa Pharmac
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Morita Hiroshi
Faculty Of Environment Engineering The University Of Kitakyushu
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Thomas Noel
Department Of Chemistry Faculty Of Science University Of Malaya
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Mohamad Khalit
Department of Pharmacy, Faculty of Medicine, University Malaya
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Litaudon Marc
Institut de Chimie de la Substances Naturelles, Centre Nationale de la Recherches Scientifique, France
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