Fulminant Myelopathy following Neurogenic Proximal Weakness Associated with Human T-Cell Lymphotropic Virus Type I Infection
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概要
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We report a patient with human T-cell lymphotropic virus type I (HTLV-I) infection, who presented with proximal extremity neurogenic muscular weakness followed by fulminant myelopathy, but with no upper motor symptoms. The symptoms were inconsistent with the World Health Organization or El Escorial criteria for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) or amyotrophic lateral sclerosis (ALS). This case indicates that fulminant myelopathy without upper motor neuronal symptoms may occur long after the onset of HTLV-I-associated neurogenic proximal muscular weakness. Additionally, we report that treatment with high-dose steroid pulse therapy partially improves symptoms of lightning pain and sensory disturbance.
著者
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Uchino Makoto
Department Of Neurology Graduate School Of Medical Sciences Kumamoto University
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Hirano Teruyuki
Department Of Neurology Graduate School Of Medical Science Kumamoto University
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Yamashita Satoshi
Department Of Biochemistry And Engineering Graduate School Of Engineering Tohoku University
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Ueda Akihiko
Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
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Hirahara Tomoo
Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
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Yamashita Satoshi
Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
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Kimura En
Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
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