Evaluation of Myocardial Changes in Familial Amyloid Polyneuropathy after Liver Transplantation
スポンサーリンク
概要
- 論文の詳細を見る
Objective The progression of cardiac amyloidosis is a prognostic factor after liver transplantation (LT) in familial amyloid polyneuropathy (FAP). The aim of this study was to assess myocardial changes in FAP amyloidgenic transthyretin (ATTR) Val30Met after LT. Patients and Methods Twelve Japanese FAP ATTR Val30Met patients who underwent LT and were followed for more than 2 years, were examined with serial echocardiography after LT. Serum BNP levels were measured in 9 patients. Results A significant increase in mean left atrial diameter and interventricular septal thickness was observed after LT. The increase in left atrial diameter was correlated with the presence of granular sparkling echo (GSE) at preoperative examination. Serum brain natriuretic peptide (BNP) levels in patients with left atrial diameter dilation (152.0±157.6 pg/mL) were higher than in those without left atrial diameter dilation (32.0±30.0 pg/mL). Conclusion LAD and IVS were significantly increased after LT compared with preoperative examinations in Japanese FAP ATTR Val30Met patients. BNP is an important biochemical indicator of myocardiac dysfunction in FAP patients. GSE is a useful echocardiographic marker to predict cardiac amyloidosis after LT.
著者
-
Horibata Yoko
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
-
Yamashita Taro
Department Of Molecular Preventive Medicine School Of Medicine And Crest University Of Tokyo
-
Uchino Makoto
Department Of Neurology Graduate School Of Medical Sciences Kumamoto University
-
Ueda Mitsuharu
Department Of Diagnostic Medicine Graduate School Of Medical And Pharmaceutical Sciences Kumamoto Un
-
Ando Yukio
Department Of Diagnostic Medicine Graduate School Of Life Sciences Kumamoto University
-
Okamoto Sadahisa
Department Of Medicine Umea University Hospital
-
Obayashi Konen
Department Of Diagnostic Medicine Graduate School Of Medical Sciences Kumamoto University
-
Horibata Yoko
Department of Diagnostic Medicine, Graduate School of Medical Sciences, Kumamoto University
-
Misumi Yohei
Department of Neurology, Graduate School of Medical Sciences, Kumamoto University
関連論文
- FAP is a Candidate Disease in Patients with Undetermined Polyneuropathy
- Transthyretin-related familial amyloidotic polyneuropathy—Progress in Kumamoto, Japan (1967–2010)—
- A Case of Familial Amyloid Polyneuropathy due to Phe33Val TTR with Vitreous Involvement as the Initial Manifestation
- Waveform of Ophthalmic Artery Doppler Flow Predicts the Severity of Systemic Atherosclerosis
- Severe congestive heart failure with cardiac liver cirrhosis 10 years after orthotopic liver transplantation for familial amyloidotic polyneuropathy
- The Severity of Minamata Disease Declined in 25 Years : Temporal Profile of the Neurological Findings Analyzed by Multiple Logistic Regression Model
- Inhibitory Effect of α-Tocopherol on Methylmercury-Induced Oxidative Steress
- Clinical Investigation of the Lesions Responsible for Sensory Disturbance in Minamata Disease
- PJ-743 Plasma Levels of Brain Natriuretic Peptide before Percutaneous Coronary Interventions Predicts Subsequent Major Adverse Cardiac Events(Coronary revascularization, PCI-23 (IHD) PJ127,Poster Session (Japanese),The 70th Anniversary Annual Scientific M
- OJ-166 Elevated Plasma Levels of Midkine in Patients with Coronary Artery Disease and Chronic Kidney Diseases(OJ28,Kidney/Renal Circulation/CKD 1 (H),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-397 Prognostic Significance of B-type Natriuretic Peptide is Impacted by the Presence of Diabetes Mellitus in Patients with Coronary Artery Disease(Neurohumoral factors-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Azelnidipine, a long-acting calcium channel blocker, could control hypertension without decreasing cerebral blood flow in post-ischemic stroke patients. A ^I-IMP SPECT follow-up study
- Salivary Chromogranin A: Useful and Quantitative Biochemical Marker of Affective State in Patients with Amyotrophic Lateral Sclerosis
- Distribution of Dystrophin and Dystrophin-Associated Protein 43DAG(β-dystroglycan) in the Central Nervous System of Normal Controls and Patients with Duchenne Muscular Dystrophy
- Pulmonary vein (PV) stenosis after radiofrequncy catheter ablation(RFCA) for atrial fibrillation (AF) originating from PV
- PE-040 Prevalence of Senile Systemic Amyloidosis in Japanese(PE007,Preventive Medicine/Epidemiology/Education 1 (H),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Benefit of Adding Pioglitazone to Successful Statin Therapy in Nondiabetic Patients With Coronary Artery Disease
- Nitric Oxide Synthase Activity in Human Lung Cancer
- Reuse of a Japanese Familial Amyloidotic Polyneuropathy Patient's Liver for a Cancer Patient: The Domino Liver Transplantation Procedure
- Familial Multiple Trichoepithelioma Associated With Subclavian-Pulmonary Collateral Vessels and Cerebral Aneurysm
- PJ-698 Tight Heart Rate Control improves the outcome of medical treatment in patients with type B acute aortic dissection(Peripheral circulation/Vascular disease-7, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Complementary Assembly of Heterogenous Peptides into Amyloid Fibrils and Their Catalytic Function
- Fulminant Myelopathy following Neurogenic Proximal Weakness Associated with Human T-Cell Lymphotropic Virus Type I Infection
- Comprehensive gene expression profile of human activated T_h1-and T_h2-polarized cells
- A Follow up Study on the Consequences of VWF Patients in Workers Using Chain Saws in Japanese National Forests
- PJ-635 Accumulation of Carotid Atheroma in Patients with Coronary Spastic Angina Presenting Angiographical Normal Coronary Arteries(Atherosclerosis, clinical-13 (H) PJ107,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japa
- Lower urinary tract dysfunction in type 1 familial amyloidotic polyneuropathy in Kumamoto, Japan
- High-resolution ultrastructure of amyloid fibrils in familial amyloid polyneuropathy
- Midkine in plasma as a novel breast cancer marker
- Significant Correlation of Nitric Oxide Synthase Activity and p53 Gene Mutation in Stage I Lung Adenocarcinoma
- Evaluation of Myocardial Changes in Familial Amyloid Polyneuropathy after Liver Transplantation
- Two Cases of Hemiballism-hemichorea with T1-weighted MR Image Hyperintensities in Patients with Hyperglycemia
- Progress of Diagnosis of Acute Stroke
- A Unique Case of Sporadic Creutzfeldt-Jacob Disease Presenting as Progressive Supranuclear Palsy
- Spontaneous Dissection Associated with Proximal Vertebral Artery Anomaly
- Change in the Age of Onset in Patients with Familial Amyloidotic Polyneuropathy Type I
- Brain Abscess Caused by Pulmonary Arteriovenous Fistulas without Rendu-Osler-Weber Disease
- Blood pressure overshoot after tilt reversal in patients with familial amyloidotic polyneuropathy
- Atherothrombotic brain infarction in a patient with pachydermoperiostosis
- Familial amyloidotic ployneuropathy(ATTR Val30Met) with widespread cerebra lamyloid angiopathy and lethal cerebral hemorrhage
- 1 Clinical Assessment of Plaque Stabilization by Quantitative Carotid Ultrasound(New Insight and Therapeutic Strategy for Plaque Stabilization, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Late onset type I familial amyloidotic polyneuropathy : Presentation of three autopsy cases in comparison with 19 autopsy cases of the ordinary type
- Liver transplantation and new therapeutic approaches for familial amyloidotic polyneuropathy (FAP)
- Essential Role of Definitive LDL-Cholesterol Reduction by Statin, but not Pleiotropic Effects, on Achievement of Plaque Stabilization (Lipid Disorders 5 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Reduced expression of ubiquitin ligase FBXW7 mRNA is associated with poor prognosis in breast cancer patients
- Multicenter evaluation of prototype real-time PCR assays for Epstein-Barr virus and cytomegalovirus DNA in whole blood samples from transplant recipients
- Manifestations of Transthyretin-Related Familial Amyloidotic Polyneuropathy : Long-Term Follow-Up of Japanese Patients After Liver Transplantation
- Epilepsy and Takotsubo Cardiomyopathy: A Case Report
- Renal amyloidosis caused by apolipoprotein A-II without a genetic mutation in the coding sequence
- Oral Intake 6 Months after Acute Ischemic Stroke
- Paraneoplastic Limbic Encephalitis Caused by Ovarian Teratoma with Autoantibodies to Glutamate Receptor
- Cardioembolic Stroke Followed by Isolated Celiac Artery Thromboembolism
- Efficacy of Edaravone in Cardioembolic Stroke
- Acute Ophthalmoparesis Accompanied with Influenza A Infection
- Stroke and Ventricular Dysfunction in a Patient with Isolated Left Ventricular Noncompaction
- Factors Influencing Pre-Hospital Delay after Ischemic Stroke and Transient Ischemic Attack
- Signal Change of the Substantia Nigra on Diffusion-Weighted Imaging Following Striatal Infarction