Benefit of Adding Pioglitazone to Successful Statin Therapy in Nondiabetic Patients With Coronary Artery Disease
スポンサーリンク
概要
- 論文の詳細を見る
Background Pioglitazone added to successful statin therapy may be beneficial for coronary artery disease (CAD) patients without diabetes mellitus. Methods and Results Fourteen individuals optimally treated with statin for >6 months were randomized to a pioglitazone or control group. Pioglitazone significantly improved insulin resistance, reduced high-sensitivity C-reactive protein, increased high-molecular-weight adiponectin and high-density lipoprotein cholesterol levels. Ultrasound echogenicity of carotid atheroma assessed by integrated backscatter was significantly increased by pioglitazone and correlated with adiponectin levels. Conclusion Adding pioglitazone to successful statin therapy may be an effective therapeutic strategy for patients with CAD.
- 社団法人日本循環器学会の論文
- 2008-06-20
著者
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Ogawa Hisao
Department of Cardiology, Kumamoto University
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Yasujima Minoru
Kobe University
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Sugiyama Seigo
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Matsuzawa Yasushi
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Nozaki Toshimitsu
Graduate Sch of Medical Sciences, Kumamoto University
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Sugiyama Seigo
Department Of Cardiovascular Medicine Graduate School Of Medical Science Kumamoto University
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Mizuno Yuji
Division Of Cardiology Kumamoto Aging Research Institute
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Matsuzawa Y
Sumitomo Hospital
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Nozaki Toshimitsu
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Sugamura Koichi
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Ogawa Hisao
Kumamoto University
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Nozaki Toshimitsu
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Yamagishi Masakazu
Sumitomo Hospital
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Matsuzawa Y
Department Of Metabolic Medicine Graduate School Of Medicine Osaka University
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HORIBATA Yoko
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Ogawa Hisao
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Matsuzawa Yuji
Division Of Cardiovascular Medicine Kanazawa University Graduate School Of Medicine
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Horibata Yoko
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Horibata Yoko
Department Of Diagnostic Medicine Graduate School Of Medical Sciences Kumamoto University
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Moriyama Yasushi
Division Of Cardiology Kumamoto Central Hospital
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Ogawa Hisao
Department Cardiovascular Medicine Kumamoto University:division Of Intensive Care Unit Kumamoto Univ
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Sugamura Koichi
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Yamasaki Masao
Department Of Cardiovascular Medicine The Graduate School Of Medicine The University Of Tokyo
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Matsuzawa Yuji
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Morikami Yasuhiro
Department Of Cardiology Japanese Red Cross Kumamoto Hospital
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Matsuzawa Yuuji
Department Of Cardiology Sumitomo Hospital
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Matsuzawa Yasushi
Department Of Cardiology Kumamoto University School Of Medicine
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