椎体における水分子拡散の解析 : ファントムにおける検討

概要

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The purpose of our study is to evaluate restricted diffusion of the water molecules caused by the trabecular bone structure of the vertebra using a phantom. On a 1.5-T MRI, single shot diffusion echo planar imaging was used with b factors of 0, 500, and 1000s/mm2, effective TE of 80 ms, and TR of 2000ms. We determined ADC values with an original phantom, which consists of sponges with different space diameters and dry vertebral bone into the container filled with pure water We assessed the effects of values (0, 500, 1000s/mm2) and acquisition matrix (64×64, 128×128, 256×256) . ADC of the sponge increased as space diameter due to change in restricted diffusion of the water molecules, and was the same level of the dry vertebral bone. Moreover, ADC varied with b values and matrix sizes. Our original phantom enables to analyze restricted diffusion, and ADC is affected by the trabecular bone structure.
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