Uterine Adenocarcinoma with Prominent Desmoplasia in a Geriatric Miniature Pig
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概要
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A 10-year-old miniature sow was died, showing inappetence and weight loss. Grossly, neoplastic enlargement of the uterus was found. Histopathologically, the lesions consisted of acinar, ductular and cystic proliferations of mono- and multilayered epithelial cells; these cells reacted immunohistochemically strongly with three different cytokeratin antibodies, and occasionally to vimentin. Myofibroblastic desmoplastic cells, positive to α-smooth muscle actin, were present among neoplastic cells. Metastatic lesions were seen in the lungs and liver. Based on these findings, a diagnosis of uterine adenocarcinoma with marked desmoplasia was made. This case is the second report of uterine adenocarcinoma in the miniature pig.
著者
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KUWAMURA Mitsuru
Laboratory of Veterinary Pathology, Osaka Prefecture University
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Yamate Jyoji
Laboratory Of Veterinary Pathology Life And Environmental Sciences Osaka Prefecture University
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Izawa Takeshi
Laboratory Of Plant Molecular Genetics Nara Institute Of Science And Technology
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Kuwamura Mitsuru
Vet. Pathol. Osaka Pref. Uni.
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GOLBAR Hossain
Laboratory of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University
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ITO Shu
Adventure World AWS Co., Ltd.
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Kuwamura Mitsuru
Laboratory Of Veterinary Pathology Osaka Prefecture University
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