A Rhabdomyosarcoma Arising in the Larynx of a Dog
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概要
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A neoplastic nodular lesion, 2 x 3 cm in diameter, was found in the larynx of a 6-year-old spayed female dog. The tumor was ill-circumscribed, consisting histologically of large round cells with abundant cytoplasm interspersed with small round cells with less cytoplasm and occasional multinucleated cells (myotubes). Immunohistochemically, tumor cells were positive for myoglobin, desmin and vimentin in varying degrees, but negative for S-100 protein, GFAP or cytokeratin. Cytoplasmic myofilaments/myofibrils with a dense Z-line-like structure were seen, the fine structures of which were complemented by PTAH stain. Based on these findings, the tumor was diagnosed as a rhabdomyosarcoma, a very rare tumor in the larynx of dogs.
著者
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KUWAMURA Mitsuru
Laboratory of Veterinary Pathology, Osaka Prefecture University
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Yamate Jyoji
Laboratory Of Veterinary Pathology Life And Environmental Sciences Osaka Prefecture University
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Izawa Takeshi
Laboratory Of Plant Molecular Genetics Nara Institute Of Science And Technology
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Murai Fumi
Laboratory of Veterinary Pathology, Osaka Prefecture University
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Akiyoshi Hideo
Laboratory of Veterinary Surgery, Osaka Prefecture University
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Shimizu Junichiro
Laboratory of Veterinary Surgery, Osaka Prefecture University
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Ohashi Fumihito
Laboratory of Veterinary Surgery, Osaka Prefecture University
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Kuwamura Mitsuru
Laboratory Of Veterinary Pathology Osaka Prefecture University
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