Spontaneous Peritoneal Malignant Mesothelioma in a Geriatric Japanese Macaque (Macaca fuscata)
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概要
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A 28.5-year-old female Japanese macaque (Macaca fuscata) was euthanatized because of abdominal distension due to severe ascites. Nodular lesions of varying sizes up to 5 mm in diameter were distributed diffusely on the surface of the omentum, mesentery and parietal peritoneum. No neoplastic masses were detected in any visceral organ. The nodules were composed of proliferation of mono- or multi-layered epithelial-like cells occasionally showing papillary growth and sheets of small round or polygonal cells. Signet ring-like cells and tubular structures were occasionally present. Neoplastic cells were strongly positive to cytokeratin, and occasionally to vimentin. Based on gross and histopathological findings, this tumor was diagnosed as an epithelial type of peritoneal malignant mesothelioma, the first reported case in the non-human primates.
- 社団法人 日本実験動物学会の論文
著者
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KUWAMURA Mitsuru
Laboratory of Veterinary Pathology, Osaka Prefecture University
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YAMATE Jyoji
Laboratory of Veterinary Pathology, Graduate School of Agriculture and Biological Sciences, Osaka Pr
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Yamate Jyoji
Laboratory Of Veterinary Pathology Life And Environmental Sciences Osaka Prefecture University
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TOMITA Akitada
Laboratory of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University
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MITSUNAGA Fusako
Molecular Biology Section, Department of Cellular and Molecular Biology, Primate Research Institute,
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NAKAMURA Shin
Molecular Biology Section, Department of Cellular and Molecular Biology, Primate Research Institute,
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Kuwamura Mitsuru
Laboratory Of Veterinary Pathology Osaka Prefecture University
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Yamate Jyoji
Laboratory Of Veterinary Pathology Division Of Veterinary Sciences Graduate School Of Life And Environmental Sciences Osaka Prefecture University
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MITSUNAGA Fusako
Molecular Biology Section, Department of Cellular and Molecular Biology, Primate Research Institute, Kyoto University
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