Combined Hepatocellular-Cholangiocarcinoma in a Yellow-Headed Amazon (Amazon aoratrix)
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概要
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A 9-year-old male Yellow-headed Amazon (Amazon aoratrix) with a history of anorexia and vomiting died of a liver tumor. The tumor consisted of neoplastic cells with hepatocellular and cholangiocellular differentiations and their intermingled areas. Neoplastic hepatocytes showed islands or trabecular growth with vacuolated eosinophilic cytoplasm. Cells showing biliary differentiation formed ducts or tubules lined by cytokeratin AE1/AE3-positive epithelia, accompanied by desmoplasia consisting of myofibroblasts reacting to α-smooth muscle actin and desmin. The tumor was diagnosed as a combined hepatocellular-cholangiocarcinoma, which is very rare in the avian.
著者
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SASAI Hiroshi
Kitasuma Animal Hospital
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Izawa Takeshi
Laboratory Of Plant Molecular Genetics Nara Institute Of Science And Technology
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Kuwamura Mitsuru
Laboratory Of Veterinary Pathology Osaka Prefecture University
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Yamate Jyoji
Laboratory Of Veterinary Pathology Division Of Veterinary Sciences Graduate School Of Life And Environmental Sciences Osaka Prefecture University
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Fujita Daisuke
Kitasuma Animal Hospital Kobe City
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SASAI Hiroshi
Kitasuma Animal Hospital, Kobe city, Hyogo 654–0131, Japan
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IZAWA Takeshi
Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1–58 Rinku-ourai-kita, Izumisano city, Osaka 598–8531, Japan
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DENDA Yuki
Kitasuma Animal Hospital, 9-5-8 Yokoo, Suma-ku, Kobe City, Hyogo 654-0131, Japan
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SETO Eiko
Kitasuma Animal Hospital, 9-5-8 Yokoo, Suma-ku, Kobe City, Hyogo 654-0131, Japan
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KUWAMURA Mitsuru
Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1–58 Rinku-ourai-kita, Izumisano city, Osaka 598–8531, Japan
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TENNAKOON Anusha
Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1–58 Rinku-ourai-kita, Izumisano city, Osaka 598–8531, Japan
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