Detection of Babesia gibsoni by Reaction of Phage Display Single Chain Antibodies with P50 Proteins
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概要
- 論文の詳細を見る
Babesia gibsoni (B. gibsoni) is a tick-borne hemoprotozoan parasite, which causes piroplasmosis in dogs. Diagnosis of canine babesiosis is commonly carried out using Giemsa-stained thin blood smears. However, at low levels of infection, it is difficult to detect Babesia organisms by observation of Giemsa-stained thin blood smears. We constructed a monoclonal phage display single chain antibody (scFv) against a B. gibsoni merozoite antigen, P50 protein. Intraerythrocytic B. gibsoni organisms are clearly stained using this antibody. The monoclonal scFv facilitated the detection of B. gibsoni organisms in canine blood samples.
- 社団法人 日本獣医学会の論文
著者
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GOO Youn-Kyoung
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Me
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Takashima Yasuhiro
Department Of Information And Media The University Of Kitakyushu
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Xuan Xuenan
National Research Center For Protozoan Diseases Obihiro University Of Agriculture And Veterinary Med
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KITOH Katsuya
Department of Veterinary Parasitological Diseases, Gifu University
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Nishikawa Yoshifumi
National Research Center For Protozoan Diseases Obihiro University Of Agriculture And Veterinary Med
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HIROSE Yoshino
Department of Veterinary Parasitological Diseases, Gifu University
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MATSUHIRA Saeka
Department of Veterinary Parasitological Diseases, Gifu University
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BATANOVA Tatiana
Department of Veterinary Parasitological Diseases, Gifu University
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TERKAWI Mohamad
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Me
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Goo Youn-kyoung
National Research Center For Protozoan Diseases Obihiro University Of Agriculture And Veterinary Med
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Terkawi Mohamad
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine
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KITOH Katsuya
Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University
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HIROSE Yoshino
Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University
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NISHIKAWA Yoshifumi
National Research Center for Protozoan Deseases, Obihiro University of Agriculture and Veterinary Medicine
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GOO Youn-Kyoung
National Research Center for Protozoan Deseases, Obihiro University of Agriculture and Veterinary Medicine
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XUAN Xuenan
National Research Center for Protozoan Deseases, Obihiro University of Agriculture and Veterinary Medicine
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