Post-dauer Life Span of Caenorhabditis Elegans Dauer Larvae Can be Modified by X-irradiation
スポンサーリンク
概要
- 論文の詳細を見る
The time spent as a dauer larva does not affect adult life span in Caenorhabditis elegans, as if aging is suspended in this quiescent developmental stage. We now report that modest doses X-irradiation of dauer larvae increased their post-dauer longevity. Post-irradiation incubation of young dauer larvae did not modify this beneficial effect of radiation. Conversely, holding dauer larvae prior to irradiation rendered them refractory to this X-radiation-induced response. We present a model to explain these results. These experiments demonstrate that dauer larvae provide an excellent opportunity to study mechanisms by which X irradiation can extend life span.
著者
-
Miyazawa Masaki
Department Of Immunology Kinki University School Of Medicine
-
Yasuda Kayo
Teaching And Research Support Center Tokai University School Of Medicine
-
Ishii Naoaki
Department Of Molecular Biology School Of Medicine Tokai University
-
Onodera Akira
Department Of Molecular Life Science Tokai University School Of Medicine
-
Ishii Takamasa
Department Of Molecular Life Science Tokai University School Of Medicine
-
HARTMAN Philip
Biology Department, Texas Christian University
-
Yanase Sumino
Department Of Health Science Daito Bunka University School Of Sports & Health Science:department
-
Ishii Takamasa
Department of Molecular Life Science, Tokai University School of Medicine
関連論文
- Radiation Biology of Caenorhabditis elegans : Germ Cell Response, Aging and Behavior
- An Up-to-Date Anti-Cancer Treatment Strategy Focusing on HIF-1α Suppression : Its Application for Refractory Ovarian Cancer
- IIB-01 Expression of Hypoxia-related markers, GLUT-1 and HIF-1 alpha, in the ovarian tumors : association with histology and tumor grade(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- IA-20 Expression analysis of Cocaine- and amphetamine-regulated transcript (CART), leptin, orexin and neuropeptide Y in the smoking-treated rat pituitary and hypothalamus(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- II-C-28 Effects of smoking on expression of Cocaine-and Amphetamine-Regulated Transcript(CART) peptides(THE 45TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- Locomotion - Learning Behavior Relationship in Caenorhabditis elegans Following γ-Ray Irradiation
- Three Dimensional XY Critical Behavior of Heat Capacity at Normal-Incommensurate Phase Transition in Rb_2ZnCl_4
- New Phase Transition in Ferroelectric (CH_3NHCH_2COOH)_3CaCl_2 at Low Temperatures
- Critical Behaviour of Specific Heat in Ferroelectric K_2ZnCl_4 and (NH_4)_2BeF_4 at Normal-Incommensurate Phase Transition
- Ferroelectric Properties in Piezoelectric Semiconductor Zn_M_xO (M=Li, Mg)
- Dielectric Study in K_2TeO_3 : A New Ferroelectric
- A low cost and quick assay system using the free-living nematode Caenorhabditis elegans to determine the effects of Kampo medicines on life span
- Close Association between Fas Ligand (FasL; CD95L)-positive Tumor-associated Macrophages and Apoptotic Cancer Cells along Invasive Margin of Colorectal Carcinoma: A Proposal on Tumor-Host Interactions
- Post-dauer Life Span of Caenorhabditis Elegans Dauer Larvae Can be Modified by X-irradiation
- Post-dauer Life Span of Caenorhabditis Elegans Dauer Larvae Can be Modified by X-irradiation
- Hyperoxia Exposure Induced Hormesis Decreases Mitochondrial Superoxide Radical Levels via Ins/IGF-1 Signaling Pathway in a Long-lived age-1 Mutant of Caenorhabditis elegans
- Thermal and Dielectric Properties of a New Ferroelectric LaBGeO_5
- Phenotypic Properties of C. elegans Defective in Uracil-DNA Glycosylase Activity
- Cloning and Characterization of Uracil-DNA Glycosylase Gene of Caenorhabditis elegans
- 144 Establishment of a cultured mice cell with the superoxide anion (O_2^-) overproduction from mitochondria(Redox regulation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- Li-Concentration Dependence of Micro-Raman Spectra in Ferroelectric-Semiconductor Zn_Li_xO
- Optical Phonons in Ferroelectric-Semiconductor Zn_Li_O Single Crystal Studied by Micro-Raman Scattering : Condensed Matter: Electronic Properties, etc.
- Micro-Raman Scattering Study of the Ferroelectric Phase Transition in Tb_2(MoO_4)_3 in the Frequency Region of MoO_4 Internal Modes
- Crystal Structure of High-Temperature Paraelectric Phase in Bi-Layered Perovskite Sr_Bi_Ta_2O_9
- Thermal and Structural Studies of Phase Transitions in Layered Perovskite SrBi_2Ta_2O_9
- Linear Birefringence Study on the Phase Transition of K_2TeO_3
- On the High Pressure Phases VI and VII in Thiourea
- Therapeutic strategy targeting the mTOR-HIF-1α-VEGF pathway in ovarian clear cell adenocarcinoma
- A mutation in a mitochondrial electron transport gene causing oxidative stress and aging in C. elegans
- The Role of Mitochondrial Superoxide Anion (O_2^-) on Physiological Aging in C57BL/6J Mice
- Oxygen-Sensitive Mutants of the Nematode Caenorhabditis Elegans and Aging(The 4th Joint Symposium between Tokai University School of Medicine and Semmelweis University School of Medicine 7-9, June, 1993, Budapest)
- Charge Properties of Bi-Rich Strontium Bismuth Tantalate Thin Films
- Dielectric and Optical Studies of the Low-Temperature Phase in NaNbO_3: Effect of Manganese Dopant
- Crystal Structure of the High Pressure Phase VI of Thiourea : Condensed Matter: Structure, etc.
- X-Ray Study of Crystal Structures and Phase Transition in Ferroelectric Ammonium Fluoberyllate (NH_4)_2BeF_4
- Structural Changes and Ferroelectricity in Bi-Layered SrBi_2Ta_2O_9
- Molecular Mechanism of Life Span Deteminatio
- Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300
- Reexamination of Super-Lattice Structure and Diffuse Scatterings in (NH_4)_2BeF_4
- Cloning of the Oxidative Stress-responsive Genes in Caenorhabditis elegans
- Analysis of mTOR Inhibition-Involved Pathway in Ovarian Clear Cell Adenocarcinoma
- Effect of 5-Fluorodeoxyuridine on Reproduction and Aging in a Strain of Free-living Nematodes, Rhabditidae tokai
- Comparison of Argininosuccinate Synthetase from Young and Old Rat Livers
- Ultraviolet Photoexcited Soft Mode Dynamics in Quantum Paraelectrics KTaO3 Doped with Nickel
- Dielectric and Thermal Properties of Single-Crystalline CaCu3Ti4O12 at High Temperatures
- Ferroelectric Phase Transition and Photoinduced Cooperative Phenomena in Bi-Layered Perovskite Pb2Bi4Ti5O18 Ceramics Studied by Brillouin Scattering
- Long Term Prognostic Implications of Expression of Glucose Transporter-1 and Hexokinase II in Patients with Stage I Uterine Leiomyosarcoma
- Granulosa cell tumor with activated mTOR-HIF-1α-VEGF pathway
- Li-Substitution Effect and Ferroelectric Properties in Piezoelectric Semiconductor ZnO
- Phase Transition in Bi-Layered Oxides with Five Perovskite Layers
- Structural Study of Intermediate Phase in Layered Perovskite SrBi2Ta2O9 Single Crystal
- Dielectric Properties and Phase Transition in CaCu3Ti4O12 at High Temperatures