非等方拡散法を用いたRI骨シンチ画像の平滑化に関する実験的検討

概要

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Bone scintigraphy is the most effectively applied examination in finding temporal transfer of cancerous diseases such as breast cancer to bone. Although diagnosis of bone scintigrams has been based commonly on inspection by eyes, it may be more informative by introducing quantitative evaluation and automatic detection of abnormal concentration of RI agents. For this purpose, a first task has been set as noise removal, because the high noise level of the scintigrams can be obstructive to machine processing. Under the condition of low resolution, we have studied the feasibility of anisotropic diffusion and its variant of the total variation (TV) minimization method. Several methods have been applied to noisy test patterns in order to determine optimal values of the parameters. The Tsuji diffusion with and without regularization and the TV minimization resulted promising with a few thousands of repetitions with minimal errors and fair visual appearances. When applied to clinical bone scintigrams, they resulted promising visual appearances with about a hundred repetitions.
医用画像情報学会の論文