^<99m>Tc-GSA肝シンチグラフィの視覚的評価に影響を及ぼすキャリブレーションカーブの検討

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With a view to improving the correlation of liver scintigraphy using ^<99m>Tc-DTPA-galactosyl human serum albumin(GSA)with hepatic function as indicated by indices such as LHL15, HH15, and laboratory data, the present study was carried out to set up a calibration curve(CC)for visual analysis. The application of 7 patterns of CC with different settings to a 1-min image(5 to 6 minutes after radiotracer injection)in 98 cases led to the preparation of 686 images whose correlation with hepatic function was examined by 15 observers via the grade classification of a five-point scoring system using visual analysis. The grade classification was as follows : grade 1(faint cardiac blood-pool image), grade 2(slight cardiac blood-pool image compared with liver uptake), grade 3(almost the same appearance of cardiac blood-pool image and that of liver uptake), grade 4(intense cardiac blood-pool image associated with possible liver uptake), and grade 5(very slight liver uptake). The five-point scoring system could be used for CC slopes of 4.21, 4.79 and 2.79(the above coorelation was strongest for 4.21). The significance of inter-grade group differences in ICGR15, LHL15 and heart/liver ratio was examined according to slope. With the CC slope of 4.21, a significant inter-grade group difference was observed between grades 1 and 2, grades 2 and 3, grades 3 and 4, grades 4 and 5. In conclusion, when the value of the CC slope was 4.2, it was considered appropriate for grade classification on a five-point scoring system using visual analysis.
公益社団法人日本放射線技術学会の論文
1997-10-20

^<99m>Tc-GSA肝シンチグラフィの視覚的評価に影響を及ぼすキャリブレーションカーブの検討

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