^<123>I-IMPを用いた非侵襲的マイクロスフェア(NIMS)法とARG法の同時施行による比較検討

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We evaluated the significance of measurement of cerebral blood flow by the noninvasive microsphere method (NIMS) using ^<123>I-IMP in 11 patients (nine men and two women) with cerebral vascular disease. Their ages at the time of study ranged from 35 to 69 years (men, 52 years). Evaluation was done by comparison of cardiac output using ultrasonography and rCBF obtained by IMP-autoradiography (ARG). Simultaneous acqusition of images was carried out in all patients using both NIMS and IMP-ARG. Cardiac output (CO) was obtained using color Doppler ultrasonography on the same day. The values of CBF obtained by NIMS and ARG were compared, and a statistically significant differece (r=0.74) was found in the region of interest (ROI) determined to be the pulmonary artery (PA) compared with that of the right ventricle (RV). There was a significant difference (r=0.815) between the CBF values obtained from ARG and NIMS. Of interest, there was no problem with regard to the time activity curve in patients with tricuspid regurgitation (TR) 1-degree. In conclusion, our data emphasize that the NIMS technique is more useful than ARG technique.
公益社団法人日本放射線技術学会の論文
2000-07-20