Severe Legionnaires' Disease Successfully Treated Using a Combination of Fluoroquinolone, Erythromycin, Corticosteroid, and Sivelestat
スポンサーリンク
概要
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The patient was a 67-year-old man with diabetes mellitus who had been to a hot spring spa a few days before his admission. The diagnosis of Legionella pneumonia was made using a urinary antigen assay. Intravenous pazufloxacin and oral clarithromycin were started. However, despite these treatments, he developed acute respiratory distress syndrome (ARDS). He was administered the combination of intravenous pazufloxacin and erythromycin, corticosteroid, and sivelestat for two weeks. Then he was successfully recovered. The outcome suggests that treatment with corticosteroid and sivelestat, in addition to a combination of appropriate anti-Legionella antibiotics, should be considered for patients with severe Legionella pneumonia with ARDS.
著者
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KOHNO Shigeru
Department of Internal Medicine, Nagasaki University School of Medicine
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IZUMIKAWA Koichi
Department of Laboratory Medichine, Nagasaki University School of Medicine
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Yamamoto Yoshihiro
Department Of Biological Science Graduate School Of Science Hiroshima University
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Saito Atsushi
Division Of Infectious Diseases Department Of Internal Medicine Graduate School Of Medicine Universi
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Seki Masafumi
Department Of Molecular Microbiology And Immunology Nagasaki University Graduate School Of Biomedical Sciences
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Yanagihara Katsunori
Department Of Clinical Laboratory Nagasaki University Hospital
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Saito Atsushi
Division of Respiratory Diseases, Japanese Red Cross Nagasaki Genbaku Isahaya Hospital
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Kakeya Hiroshi
Division of Respiratory Diseases, Japanese Red Cross Nagasaki Genbaku Isahaya Hospital
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Ehara Naomi
Division of Respiratory Diseases, Japanese Red Cross Nagasaki Genbaku Isahaya Hospital
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Fukushima Kiyoyasu
Division of Respiratory Diseases, Japanese Red Cross Nagasaki Genbaku Isahaya Hospital
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Seki Masafumi
Department of Cardiology, Kitakyushu City Yahata Hospital
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