Multiple Immune Abnormalities in a Patient with Idiopathic CD4+ T-Lymphocytopenia
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概要
- 論文の詳細を見る
Idiopathic CD4+ T-lymphocytopenia (ICL) is a new disease entity characterized by CD4+ T-lymphocyte depletion without evidence of HIV infection. We report a 27-year-old ICL patient with a long history of multiple immune abnormalities. His CD4+ T-lymphocyte count started to decrease after generalized lymphadenopathy of an unknown cause at age 3. He satisfied the criteria for ICL at age 9, and the decreased CD4+ Tlymphocyte count persisted for more than 18 years. This is probably the first childhood-onset ICL case in which the trigger event for the development was known together with the patient's autoimmune background.
著者
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TSURUDA Kazuto
Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences
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HASEGAWA Hiroo
Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences
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Kamihira Shimeru
Department Of Laboratory Medicine Nagasaki University Graduate School Of Biomedical Sciences
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Tsukasaki Kunihiro
Department Of Hematology And Oncology Nagoya University Graduate School Of Medicine
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Yamada Yasuaki
Department Of Clinical Laboratory Nagasaki University Hospital
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OKADA Masahiko
Department of Applied Molecular Bioscience, Graduate school of Bioagricultural Science, Nagoya Unive
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Kamitamari Akira
Department Of Pediatrics Sasebo City General Hospital
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Moriuchi Hiroyuki
Department Of Molecular Microbiology And Immunology Nagasaki University Graduate School Of Biomedica
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Yanagihara Katsunori
Department Of Clinical Laboratory Nagasaki University Hospital
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Yanai Masanori
Yanai Children's Clinic
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Tsuruda Kazuto
Department of Laboratory Medicine, Nagasaki University Hospital
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Tsukasaki Kunihiro
Department of Hematology, Nagasaki University Hospital
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Hasegawa Hiroo
Department of Laboratory Medicine, Nagasaki University Hospital
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Hano Osamu
Hano Clinic
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Kamihira Shimeru
Department of Laboratory Medicine, Nagasaki University Hospital
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OKADA Masahiko
Department of Applied Biological Sciences, School of Agricultural Sciences, Nagoya University
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