Idiopathic Hypereosinophilic Syndrome Presenting Acute Abdomen

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概要

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• We describe a 27-year-old man with hypereosinophilc syndrome (HES) presenting acute abdomen due to acute thrombosis of the mesenteric artery, who had a past history of eosinophilic pneumonia followed by multiple arterial thromboses of the extremities. At the recurrence of eosinophilia, he was treated with high-dose corticosteroids. Immediately after the reduction of peripheral blood eosinophils, he suddenly developed perforation of the intestine due to acute thromboses of mesenteric arteries despite sustained anticoagulation therapy. Molecular analysis demonstrated that the FIP1L1-PDGFRA fusion gene was negative. Histopathology showed thrombi and eosinophilic inflammation of arteries. It is important to recognize that HES could be a cause of acute abdomen.

• 社団法人日本内科学会の論文

著者

• Kubota Tetsuya

  Department Of Diabetes And Metabolic Disease Graduate School Of Medicine University Of Tokyo

• Taguchi Hirokuni

  Department Of Diagnostic Pathology Kochi Red Cross Hospital

• Bandobashi Kentaro

  Department Of Hematology And Respiratory Medicine Graduate School Of Kuroshio Science Kochi Universi

• Kuwayama Yoshio

  Department Of Hematology And Respiratory Medicine Kochi University

• Komatsu Naoki

  Department Of Chemistry Graduate School Of Science Kyoto University

• Kobayashi Makoto

  Department Of Agricultural Chemistry College Of Agriculture And Veterinary Medicine Nihon University

• UEMURA Yoshiki

  Department of Hematology and Respiratory Medicine, Kochi University School of Meicine

• Kubota Tetsuya

  Department of Hematology and Respiratory Medicine, Kochi Medical School, Kochi University

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