Prevention of trabecular bone loss in the mandible of ovariectomized rats
スポンサーリンク
概要
- 論文の詳細を見る
The effect of therapeutic agents on trabecular bone loss in the mandible was investigated in ovariectomized rats. Eighty-seven Wistar SPF female rats were ovariectomized (OVX) or given a sham operation (Sham), and maintained on a diet containing 0.1 % calcium. Four weeks later, groups of OVX rats were treated with estriol (E3), calcitonin (CT), etidronate, or 2-carboxyethylgermanium sesquioxide (Ge-132). The Basal group was maintained on a diet containing 1.0 % calcium, and the OVX and sham groups on a diet containing 0.1 % calcium. The trabecular bone mineral density (BMD) and trabecular bone mineral content (BMC) in 11 mandibular slices from 0.5 mm at the mesial margin of the first molar to 0.5 mm at the distal margin of the third molar, were measured using peripheral Quantitative Computed Tomography (pQCT). The BMD in the OVX group was lower than that in the Sham group, and decreased BMC was observed only in the molar region. BMD and BMC were increased in the etidronate-treated group, but only BMC was increased in the CT group. E3 treatment increased BMD and BMC; significant increases were also observed beneath the molar. Ge-132 treatment increased both BMD and BMC, especially the latter. (J. Oral Sci. 46, 75-85, 2004)
著者
-
Akimoto Yoshiaki
Department of Oral Surgery, Nihon University School of Dentistry at Matsudo
-
Kuboyama Noboru
Department Of Oral Molecular Pharmacology Nihon University School Of Dentistry At Matsudo
-
Yamane Junichi
Department Of Pharmacology Nihon University School Of Dentistry At Matsudo
-
Jiang Guizhen
Department Of Pharmacology Nihon University School Of Dentistry At Matsudo
-
Fujii Akira
Department Of Applied Chemistry Faculty Of Engineering Oita University
-
Matsumoto Hiroko
Department Of Astronomy School Of Science Kyoto University
-
Akimoto Yoshiaki
Department of Dento-Maxillofacial Surgery, Nihon University School of Dentistry at Matsudo
関連論文
- PE-310 Impaired Postprandial Vasodilatation in Metabolic Syndrome. On behalf of MEAL Investigators.(Diabetes/Obesity/Metabolic syndrome(06)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- An Unusually Large Submandibular Salivary Calculus: Case Report and Structural Analysis
- Incidence of gingival overgrowth induced by calcium channel blocker
- Midline cystic malformations of the brain : imaging diagnosis and classification based on embryologic analysis
- X-ray Phase-Contrast Imaging and X-ray Absorption Fine Structure Analysis using Parametric X-ray Radiation Generated at LEBRA, Nihon University
- Fluorescent In Situ Hybridization Analysis of Open Lactic Acid Fermentation of Kitchen Refuse Using rRNA-Targeted Oligonucleotide Probes(ENVIRONMENTAL BIOTECHNOLOGY)
- Comparative antimutagenicity of saliva and oral bacteria against mutagens
- AED Location in Public Spaces : A Case Study in Ueno Park Using Voronoi Diagrams with Obstacles(Architectural/Urban Planning and Design)
- Cryoprotective Activities of Group 3 Late Embryogenesis Abundant Proteins from Chlorella vulgaris C-27
- Osteosarcoma of the mandible in an aged person
- Diagnostic Problems of Early and Primary Lesions of Tuberculous Cervical Lymphadenitis
- Basic research for crystal composition of sialolith(Poster Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)
- Elevated levels of oxidized low density lipoprotein (ox-LDL) relate to plaque instability in diabetic patients
- Guided Bone Regeneration with Novel Bioabsorbable Membranes(Bioengineering)
- Intermittent Crystal Growth of Unusually Long Submandibular Sialolith Revealed by Micro-Focus-and Selected-Area-X-Ray Diffraction
- Langerhans Cell Histiocytosis in the Mandible : Computed Tomography and Magnetic Resonance Imaging
- Prevalence of Amlodipine-induced Gingival Overgrowth
- Effect of Oral Administration of High Advanced-Collagen Tripeptide (HACP) on Bone Healing Process in Rat
- DELETERIOUS EFFECT OF SHORT-TERM EXPOSURE TO COCA-COLA ON RATS
- 101. STUDY ON TOXICITY OF COCA-COLA (The Third Meeting for the Study of Toxic Effect)
- FETAL LIVER AND KIDNEY TOXICITIES BY ALCOHOL AND SUCROSE
- INFLUENCE OF SUGAR ON THE STRENGTH OF RAT FEMUR BONE
- Experimental Study of Bone Formation Ability with the Periosteum on Rat Calvaria
- An outbreak of Pseudomonas aeruginosa infections following thoracic surgeries occurring via the contamination of bronchoscopes and an automatic endoscope reprocessor
- Drug-induced gingival overgrowth and its tentative pharmacotherapy
- Effect of Organic Germanium Compound (Ge-132) on Experimental Osteoporosis in Rats: The Relationship Between Transverse Strength and Bone Mineral Density (BMD) or Bone Mineral Content (BMC)
- Hepatitis C virus (HCV) genotype 1b sequences from fifteen patients with hepatocellular carcinoma : the 'progression score' revisited
- Differences of Cell Growth and Cell Cycle Regulators Induced by Basic Fibroblast Growth Factor Between Nifedipine Responders and Non-responders
- Correlation among geometric, densitometric, and mechanical properties in mandible and femur of osteoporotic rats
- T Helper Cytokine Responses Induced by Nasal Immunization with Glucosyltransferase-I of Streptococcus sobrinus
- A Case of a Huge Solitary Neurofibroma Extending from the Tongue to the Floor of the Mouth
- Dental age in Japanese children using a modified Demirjian method
- Mandible bone loss in osteoporosis rats
- Peripheral Ameloblastoma Presenting as a Gingival Mass
- Endoscopic injection sclerotherapy for esophageal variceal hemorrhage in myeloproliferative disorder: Case report
- A Consideration of Papillary Squamous Cell Carcinoma of the Gingiva : A Case Study Involving the Immunohistochemistry of Proliferative Activity
- SUSCEPTIBILITY OF SWISS ALBINO MICE TO Staphylococcus aureus INFECTIONS UNDER LEAD ACETATE INFLUENCES AND THE PROTECTIVE ACTION OF YEAST EXTRACTS TO THE INFECTION (The Fourth Meeting for the Study of Toxic Effect)
- Effect of Low Level Laser Irradiation on CXCR3 Gene Expression in Rheumatoid Arthritis Joint
- Syntactic and Network Pattern Structures of City : Comparison of Grid and Meandering Street Patterns in Kyojima and Honjo(Architectural/Urban Planning and Design)
- Effects of Ovariectomy on Intestinal Alkaline Phosphatase Expression in Rats
- Interpretation of the Expansion Law of Planetary Nebulae
- Possibility of application of calcium carbonate in pulpotomy of rat molars
- Prevention of trabecular bone loss in the mandible of ovariectomized rats
- A Histopathological and Immunohistochemical Study of Cell Proliferative Activity in Epulis Osteoplastica and Epulis Fibrosa
- Influence of aging on experimental gastrointestinal motility in extraction of rat molar teeth
- Stimulation of Mesenchymal-epithelial Transition Factor (c-Met) Expression in Candida Albicans-infected Human Gingival Epithelial Cells and Rat Gingival Epithelium
- Intranasal Immunization with Porphyromonas gingivalis Outer Membrane Protein Inhibits P. gingivalis-induced Atherosclerosis in C57BL/6 Mice Fed a Hgh-fat Diet
- Vigorous cleaning and adequate ventilation are necessary to control an outbreak in a neonatal intensive care unit
- An orthopantomographic study of hypodontia in permanent teeth of Japanese pediatric patients
- The effect of IL-l.ALPHA. and nifedipine of cell proliferation and DNA synthesis in cultured human gingival fibroblasts
- Propofol Reduces Hydrogen Peroxide-Induced Apoptosis through Down-Regulating Bim Expression in Alveolar Epithelial Cells
- Serum Antibodies against Porphyromonas gingivalis GroEL are Insufficient to Induce P.gingivalis-accelerated Atherosclerosis
- Glutamine Production by Coupling with Energy Transfer: Employing Yeast Cell-Free Extracts and Gluconobacter Glutamine Synthetase
- Glutamine Production by Coupling with Energy Transfer: Employing Yeast Cells and Gluconobacter Glutamine Synthetase
- A Large Calculus in the Parotid Duct
- Augmentation of wound healing by royal jelly(RJ) in streptozotocin-diabetic rats.
- Time-course study of gastric damages in rats by anti-inflammatory drugs using a gastroscope and its quantification.
- Osteoma in Ethmoid Sinus: a case report
- Movable carcinoma in pleomorphic adenoma of the palate with a pedicle base
- Healing-promoting action of dried aluminium hydroxide gel evaluated by the method of histological measurements in acetic acid ulcer of rats.
- Healing-promoting action of teprenone, a new antiulcer agent on acetic acid ulcer in rats.
- A Case of a Natal Tooth Showing a Pediculated Polyp-like Appearance
- Mucous Retention Cyst of the Upper Lip Possibly Caused by Cavernous Hemangioma with Thrombi
- Does ScoliScore Provide More Information Than Traditional Clinical Estimates of Curve Progression?