Strain Differences to Effects of Aging on Concentrations of Amino Acids in Cerebrospinal Fluid between Sprague Dawley Rat and Wistar Kyoto Rat
スポンサーリンク
概要
- 論文の詳細を見る
Age-related alterations and differences of weights and those of amino acid concentrations in the cerebrospinal fluid (CSF) were evaluated between Sprague Dawley (SD) rats and Wistar Kyoto (WKY) rats from eight to twenty weeks of age. The weights of SD rats were heavier than WKY rats at all ages. The age-related alterations of the CSF concentration of many amino acids within each strain were significant but showed no significant trend with age. Between the strains, the concentration differences of excitatory and inhibitory amino acids were not frequent although the concentrations of arginine, alanine and threonine were significantly higher in SD rats than in WKY rats. These results suggest that the different CSF concentrations of amino acids may relate to characteristics of rat strains.
- 社団法人 日本実験動物学会の論文
- 2003-10-01
著者
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Okuda Takahiko
Department of Anesthesiology, Nara Hospital Kinki University School of Medicine
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Koga Yoshihisa
Department of Anesthesiology, Kinki University School of Medicine
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Koga Yoshihisa
近畿大学 医学部麻酔科学
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Koga Yoshihisa
Department Of Anesthesiology School Of Medicine Kinki University
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Koga Yoshihisa
Department Of Anesthesiology Kinki University School Of Medicine
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Okuda Takahiko
Department Of Anesthesiology School Of Medicine Kinki University
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Okuda Takahiko
Department Of Anesthesiology Kinki University School Of Medicine
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Okuda Takahiro
Department Of Anesthesiology School Of Medicine Kinki University
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TAKASUGI Yoshihiro
Department of Anesthesiology, School of Medicine, Kinki University
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KAWATA Keiji
Department of Anesthesiology, School of Medicine, Kinki University
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MIZUGUCHI Nobuyuki
Life Science Research Institute, School of Medicine, Kinki University
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YAMANAKA Shigeaki
Life Science Research Institute, School of Medicine, Kinki University
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WATANABE Shinsuke
Life Science Research Institute, School of Medicine, Kinki University
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Watanabe Shinsuke
Life Science Research Institute School Of Medicine Kinki University
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Kawata Keiji
Department Of Anesthesiology School Of Medicine Kinki University
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Yamanaka Shigeaki
Life Science Research Institute School Of Medicine Kinki University
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Mizuguchi Nobuyuki
Life Science Research Institute Kinki University School Of Medicine
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Mizuguchi Nobuyuki
Life Science Research Institute School Of Medicine Kinki University
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Takasugi Yoshihiro
Department Of Anesthesiology Kinki University School Of Medicine
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Takasugi Yoshihiro
Department Of Anesthesiology Kinki University Faculty Of Medicine
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Koga Yoshihisa
Department Of Anesthesiology Kinki University Faculty Of Medicine
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