High Oleic Peanut Oil Modulates Promotion Stage in Lung Tumorigenesis of Mice Treated with Methyl Nitrosourea

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概要

• 論文の詳細を見る

• This study was undertaken to estimate the effect of high-oleic peanut oil (HO) on the promotion stage of lung tumorigenesis in mice. On day 30 after methyl nitrosourea administration, dietary HO inhibited ornithine decarboxylase activity, induced the inactivation of Mek, and reduced the level of proliferating cell nuclear antigen in lungs of mice more than did high-linoleic safflower oil. A parallel effect was observed in the level of prostaglandin E2 in the lungs. These results suggest that HO suppresses the promotion stage of lung tumorigenesis in mice and that the suppression correlates to the level of PGE2.

• 社団法人　日本食品科学工学会の論文
• 2005-05-01

著者

• Sakurai Hidetoshi

  College Of Bioresource Sciences Nihon University

• Fukumoto Keiko

  Division Of Applied Food Research National Institute Of Health And Nutrition

• YAMAKI Tatsuya

  College of Bioresource Sciences, Nihon University

• NAGAMINE Isao

  College of Bioresource Sciences, Nihon University

• YANO Tomohiro

  Division of Applied Food Research, National Institute of Health and Nutrition

• MIYAHARA Mitsuyoshi

  College of Bioresource Sciences, Nihon University

• Yano Tomohiro

  Project For Complementary Factors National Institute Of Health And Nutrition

• Yano Tomohiro

  Division Of Applied Food Research National Institute Of Health And Nutrition

• Yano Tomohiro

  Division Of Applied Food National Institute Of Health And Nutrition

• Nagamine Isao

  College Of Bioresource Sciences Nihon University

• Yamaki Tatsuya

  College Of Bioresource Sciences Nihon University

• Miyahara Mitsuyoshi

  College Of Bioresource Sciences Nihon University

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