Effects of Dressing Containing Plant Sterol on Serum Cholesterol Concentration and the Safety Evaluation in Borderline or Mildly Hypercholesterolemic Japanese Subjects
スポンサーリンク
概要
- 論文の詳細を見る
In a placebo-controlled double-blind study, we examined the effects of dressing containing plant sterol (PS) on blood lipids and the safety in Japanese borderline or mildly hypercholesterolemic subjects. Fifty-nine subjects [total cholesterol (TC) concentration ≥ 200 mg/dL] were randomly divided into two groups and were given daily 15 g of dressing containing 800 mg of PS [PS(+)-group] or without PS [PS(-)-group] for 12 weeks. Every 4 weeks, fasting blood was examined and subjective symptoms were analyzed. Serum TC, low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (ApoB) concentrations did not change in the PS(-)-group, while TC and ApoB significantly decreased in the PS(+)-group at 8 and 12 weeks and LDL-C at 4, 8 and 12 weeks. Moreover, serum TC, LDL-C and ApoB concentrations were significantly lower than those of PS(-)-group at 8 and 12 weeks. Other laboratory tests were all in normal ranges and no adverse events were observed. The results indicated that PS-containing dressing decreased serum TC, LDL-C and ApoB concentrations in borderline or mildly hypercholesterolemic subjects. It is therefore proved that the dressing containing PS is helpful in maintaining blood cholesterol level normal and hence, the health of Japanese.
- 日本油化学会の論文
著者
-
Homma Yasuhiko
Department Of Internal Medicine Tokai University School Of Medicine
-
Homma Yasuhiko
Department Of Clinical Health Science Tokai University School Of Medicine
-
TAKEDA Sayaka
R&D Division, Q. P. Corporation
-
MASUDA Yasunobu
R&D Division, Q. P. Corporation
-
KUROKAWA Masanori
R&D Division, Q. P. Corporation
-
HASEGAWA Mineo
R&D Division, Q. P. Corporation
-
Masuda Y
R & D Division Q.p. Corporation
-
Masuda Yasunobu
キューピー
-
Masuda Yasunobu
R&d Div. Q.p. Corp.
-
Kurokawa Masanori
キューピー
-
Noda Mitsuhiro
R&D Division, Q.P. Corporation
-
Usuda Mika
R&D Division, Q.P. Corporation
-
Sugano Michihiro
Professor Emeritus, Kyusyu University and Prefectual University of Kumamoto
-
Sugano Michihiro
Professor Emeritus Kyushu Univ. And Prefectural Univ. Of Kumamoto
-
Kimura Mamoru
R&d Division Q.p. Corporation
-
Masuda Yasunobu
Q. P. Corporation R&d Division
関連論文
- STUDIES ON THE CLASSIFICATION OF HYPERLIPIDEMIA (X) : Proceedings of the 34th Annual Meeting of the Japanese Circulation Society (Part I)
- STUDY ON THE STRUCTURE OF GLYCERIDE IN THE ARTERIAL WALLS : Proceedings of the 34th Annual Meeting of the Japanese Circulation Society (Part I)
- Effects of Mayonnaise Containing Plant Sterol on Blood Cholesterol in Borderline or Mildly Hypercholesterolemic Japanese Subjects
- STUDIES ON THE STRUCTURE OF TRIGLYCERIDE (V) : CHANGES IN POSITIONAL DISTRIBUTION OF FATTY ACIDS IN TG AFTER FAT AND ETHANOL LOADING
- STUDY ON THE CLASSIFICATION OF HYPERTRIGLYCERIDEMIA : Proceedlngs of the 35th Annual Meetlng of the Japanese Circulation Society (part I)
- CHOLESTEROL REMOVAL FROM FIBROBLASTS OR LYMPHOCYTES BY HDL_2 AND HDL_3 : Coagulation, Arteriosclerosis : PROCEEDINGS OF THE 44th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -147-THE HIGH DENSITY LIPOPROTEIN (HDL) CHOLESTEROL AMONG JAPANESE : Fatty Metabolism : PROCEEDINGS OF THE 42nd ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Effects of Dressing Containing Plant Sterol on Serum Cholesterol Concentration and the Safety Evaluation in Borderline or Mildly Hypercholesterolemic Japanese Subjects
- Minimal Effective Dose on Serum Cholesterol Concentration and the Safety Evaluation of Dressing Containing Plant Sterol in Japanese Subjects
- Effects of Mayonnaise on Postprandial Serum Lutein/Zeaxanthin and β-Carotene Concentrations in Humans
- A Double-blind, Placebo-Controlled Study on the Effects of Mayonnaise Containing Free Plant Sterol on Serum Cholesterol Concentration ; Safety Evaluation for Normocholesterolemic and Mildly Hypercholesterolemic Japanese Subjects
- -544- EFFECTS OF LIPOLYSIS ON ESTERIFICATION AND TRANSFER OF CHOLESTEROL
- SELECTIVITY IN REMOVAL OF LOW DENSITY LIPOPROTEIN (LDL) BY PLASMAPHERESIS (PP) AND NORMALIZATION OF PLASMA LDL BY COMBINATION THERAPY WITH PP AND DRUGS IN FAMILIAL HYPERCHOLESTEROLEMIA : Atherosclerosis : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING
- Changes in Plasma Lipoprotein Levels during Medication with a Glucoside-hydrolase Inhibitor (Acarbose)
- Effect of Dietary Plant Sterols and/or Mayonnaise Supplementation on the Lipid Metabolisms in Rats
- CONVERSION OF LOW DENSITY LIPOPROTEIN 1 (LDL_1, 1.019 < d < 1.045) TO LOW DENSITY LIPOPROTEIN 2 (LDL_2, 1.045 < d < 1.063) BY HEPATIC TRIGLYCERIDE LIPASE
- Serum concentration of 27-hydroxycholesterol predicts the effects of high-cholesterol diet on plasma LDL cholesterol level
- Minimal Effective Dose of Plant Sterol on Serum Cholesterol Concentration in Japanese Subjects and Safety Evaluation of Plant Sterol Supplemented in Mayonnaise
- QRS Normalization of Bundle Branch Block by Ventricular Fusion
- An Improved Method for Removal of Antithrombin III from Post-heparin Plasma Lipase Fractions with a High Recovery Rate
- Elaidic Acid and Oleic Acid Have Opposite Effects on Serum Glucose, Insulin and Immunoglobulin Levels and Eicosanoid Production in Streptozotocin-Induced Diabetic Rats
- Cholesterol-Lowering Activity of Plant Sterol-Egg Yolk Lipoprotein Complex in Rats
- Mechanism for the Cholesterol-Lowering Action of Egg White Protein in Rats
- A Case of Moderate Hypertriglyceridemia with Apolipoprotein E Phenotype E4/3
- The Study on Phospholipid Structure in Arterial Walls
- -1357- CORONARY RISK FACTERS FOR SILENT MYOCARDIAL ISCHEMIA IN DIABETIC PATIENTS(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- FREQUENCY OF CORONARY VASOSPASUM ASSESSED BY PROVOCATION TESTS IN SILENT MYOCARDIAL ISCHEMIA OF DIABETIC PATIENTS
- Separation of Plasma Lipoproteins
- Mechanism for the Cholesterol-Lowering Action of Egg White Protein in Rats
- Mayonnaise Contributes to Increasing Postprandial Serum β-Carotene Concentration through the Emulsifying Property of Egg Yolk in Rats and Humans
- Oral Administration of Cal K_2 Containing Menaquinone-4 (Vitamin K_2) Enhances Serum r-Carboxylated Osteocalcin and Biochemical Components in the Femoral Tissues of Rats
- Study on the Transport of Fatty Acids in the Arterial Wall
- Trans Fatty Acid Content in Japanese Commercial Margarines
- Relationships between the Visceral Fat Area on CT and Coronary Risk Factor Markers
- Supplementation with 1% Energy Trans Fatty Acids Had Little Effect on Serum Cholesterol Levels in Healthy Young Japanese Women
- Assessment of Efficacy of LDL-apheresis by Recovery Process of Plasma Lipoproteins in a Patient with Homozygous Familial Hypercholesterolemia(LDL-Apheresis)
- Supplementation with 1% Energy Trans Fatty Acids Had Little Effect on Serum Cholesterol Levels in Healthy Young Japanese Women