Potencies of Phosphine Peptide Inhibitors of Mammalian Thimet Oligopeptidase and Neurolysin on Two Bacterial Pz Peptidases
スポンサーリンク
概要
- 論文の詳細を見る
Pz peptidases A and B, from a thermophile Geobacillus collagenovorans MO-1, recognize collagen-specific tripeptide units (Gly-Pro-Xaa). They share similarities in function but extremely low identities in primary sequence with mammalian thimet oligopeptidase (TOP) and neurolysin. Three phosphine peptide inhibitors that selectively inhibit TOP and neurolysin on two bacterial Pz peptidases were investigated. They showed potent inhibition of both Pz peptidases in a range from 10 to 100 nM.
- 社団法人 日本農芸化学会の論文
著者
-
Matsui Hiroshi
Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo
-
Kawasaki Akio
Department of Cardiovascular Surgery, Teikyo University School of Medicine
-
Watanabe Kunihiko
Department of Chemical Industry, Science University of Tokyo
-
TSUJIMOTO Yoshiyuki
Department of Applied Biochemistry, Kyoto Prefectural University
-
Tsujimoto Yoshiyuki
Division Of Applied Life Sciences Graduate School Of Life And Environmental Sciences Kyoto Prefectur
-
SUGIHARA Yusuke
Department of Applied Biochemistry, Kyoto Prefectural University
関連論文
- Characteristic Effects of α1-β_1,2-Adrenergic Blocking Agent, Carvedilol, on [Ca^2+]_i in Ventricular Myocytes Compared With Those of Timolol and Atenolol
- Left Ventricular Relaxation Abnormality Is Detectable by Analysis of the Relaxation Time Constant in Patients With Atrial Fibrillation
- IS005 Cell Swelling-induced Increase in Delayed-rectifier K Current is Mediated by Autocrine Release of ATP
- IS011 Evolutionally-conserved role of nuclear factor-κB in expression of inducible nitric oxide synthase gene in ventricular myocytes
- Two-stage electrodialytic concentration of glyceric acid from fermentation broth(BIOCHEMICAL ENGINEERING)
- Gene Expressions of Keratinocyte Growth Factor and Its Receptor in the Human Endometrium/Decidua and Chorionic Villi
- Posthemorrhagic Hydrocephalus in a Fetus with Severe Tachycardia
- DPJ-010 Techinical and Theoretical Evaluation of Off-pump Surgical Radiofrequency Ablation(DPJ02,Cardiovascular Surgery/CABG (IHD),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Combined surgery for ischemic cardiomyopathy : Report of a case
- PJ-397 Impact of Radiofrequency Maze Surgery on Postoperative Cardiac Function(Arrhythmia, therapy(20)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- 3 Newly Developed Papillary Muscle Plication (Sandwich Plasty) for Ischemic Mitral Regurgitation(Symposium 9 (SY-09) (M) New Insight for Treatment of Ischemic Mitral Regurgitation,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulat
- PJ-056 A Challenge for Less-invasive Surgical Treatment of Atrial Fibrillation : Off-pump Radiofrequency Ablation of Both Atria(Arrhythmia, therapy-15, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Progression of Abdominal Aortic Aneurysm After Endovascular Stent-Grafting in a Patient with Behcet's disease : Report of a Case
- Gene Expression Profiles of Prostate Cancer Cell Lines, LNCaP, PC-3 and DU-145, Assessed by cDNA Microarray
- Vitamin D receptor gene polymorphism in familial prostate cancer in a Japanese population
- Comparison of solubilization and preparation procedures for membrane-enriched proteome analysis
- Detector Chamber Systems for Measurements of Internal Conversion Electrons Usingan On-line Mass Separator,KUR-ISOL
- Surgical Treatments for Infective Endocarditis Involving Valve Annulus
- The Decay of ^Sn
- Familial Prostate Cancer in Four Brothers
- Enzymatic degradation of fibroin fiber by a fibroinolytic enzyme of Brevibacillus thermoruber YAS-1(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Molecular Determinants of Substrate Recognition in Thermostable α-glucosidases Belonging to Glycoside Hydrolase Family 13
- Decomposition of Extremely Hard-to-Degrade Animal Proteins by Thermophilic Bacteria
- Solitons in a Convective Motion of a Low-β Plasma. II
- Solitons in a Convective Motion of a Low-β Plasma
- Potencies of Phosphine Peptide Inhibitors of Mammalian Thimet Oligopeptidase and Neurolysin on Two Bacterial Pz Peptidases
- Functional Analysis of Human P5, a Protein Disulfide Isomerase Homologue
- A Single-Chain Fv Fragment 2A3 Specific for Native Lysozyme : Isolation from a Human Synthetic Phage Display Antibody Library and Characterization
- Immunohistochemical and Immunochemical Localizaiton of Heat Shock Protein 27KD in the Developing Rat Retina: The Differential
- Sunitinib Induced Immune Thrombocytopenia
- Use of a Gluconobacter frateurii Mutant to Prevent Dihydroxyacetone Accumulation during Glyceric Acid Production from Glycerol
- Effects of Transforming Growth Factor Alpha and Hepatocyte Growth Factor on Acid-Induced Damage in Rat Gastric Epithelial Cells
- Effects of Sucralfate and Its Components on Acid- and Pepsin-Induced Damage to Rat Gastric Epithelial Cells
- Potencies of Phosphine Peptide Inhibitors of Mammalian Thimet Oligopeptidase and Neurolysin on Two Bacterial Pz Peptidases
- Production of Glyceric Acid by Gluconobacter sp. NBRC3259 Using Raw Glycerol
- ESTIMATION OF PATH FLOWS AND MODIFICATION OF O-D FLOWS BASED ON PROBE VEHICLE INFORMATION AND TRAFFIC COUNTS
- Observation of Quasi-One Dimensional Proton Conductions in Molecular Porous Crystal [CoIII(H2bim)3](TMA)$\cdot$20H2O
- Bionanotechnology Approach in Material Synthesis and Device Fabrication by Applying Peptide/Protein Assemblies
- Functional roles of YPT31 and YPT32 in clotrimazole resistance of Saccharomyces cerevisiae through effects on vacuoles and ATP-binding cassette transporter(s)(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
- Effect of Voluntary Exercise on Resting Blood Pressure and Heart Rate in Rats
- Beraprost Sodium-Induced Hypotension in Two Patients After Cardiac Surgery
- Role of Brain and Peripheral Monoamine Contents on Regulating Blood Pressure Level during Application of Running Wheel Exercise Therapy for Spontaneously Hypertensive Rats(SHR)
- Photoreactions of N-Vinylcarbazole Induced by Metal Salts. VI. Cyclodimerization Catalyzed by Copper(II) Perchlorate in Aprotic Solvents
- An Adult Case with an Abnormal Right Ventricular Structure Causing Intraventricular Pressure Gradient and a History of Aphthous Stomatitis and Thrombophlebitis.
- The electroxidation of methanol in the potential region of platinum-oxygen layer.