抗カルジオリピン抗体とアフェレシス : 抗リン脂質抗体症候群とアフェレシス(<特集>膠原病とアフェレシス)

概要

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Anticardiolipin antibody and lupus anticoagulant are high-risk factors for arterial or venous thrombosis, habitual abortion, thrombocythepenia and the like(i.e., the so called antiphos- pholipid syndrome(APS)). In this paper, diagnosis and therapy for APS are documented, especially the application and effectiveness of plasmapheresis therapy for APS. Patients with catastrophic APS should have better prognosis with plasmapheresis therapy. Immunoadsorbent plasmapheresis is considered an excellent method of plasmapheresis therapy because of the good reduction rate of anticardiolipin antibodies and lupus anticoagulant, no need for albumin supply and the ability to operate with less blood volume than double-filtration plasmapheresis. A case of catastrophic APS treated by immunoadsorbent plasmapheresis is also described.
日本アフェレシス学会の論文
1997-05-31