大黄の生薬学的研究(第5報) : 各種Rheum属植物の根茎水エキスのヒト血小板凝集阻害作用について

概要

論文の詳細を見る
For the purpose of establishing a method for evaluating the quality of Rheum plants and also of finding their new medicinal uses, we investigated the effect of aqueous extracts from rhizomes of eleven different species of the genus Rheum on the human platelet aggregation induced by collagen in vitro. Of the extracts examined, an extract of Rheum tanguticum had the most potent inhibitory action on the aggregation with an IC_<50> = 0.68 ±0.20 mg/ml and those of R. hotaoense, R. lhasaense and R. alexandrae also showed a potent inhibitory activity. These extracts contained relatively high amounts of tannins, but no definite correlation was observed between the inhibitory activity on platelet aggregation and the tannin content.
日本生薬学会の論文
1991-03-20