ヨモギ属植物の利胆作用

概要

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The effects of water extracts of ten Artemisia plants [1,A. japonica THUNB. (spike, leaf) ; 2,A. apiacea HANCE (spike, leaf) ; 3,A. annua L. (spike, leaf) ; 4,A. princeps PAMP. (spike, leaf) ; 5,A. capillaris THUNB. (spike, leaf) ; 6,A. iwayomogi KITAM. (spike, leaf) ; 7,A. keiskeana MIQ. (spike) ; 8,A. feddei LAV. et VAN. (spike) ; 9,A. stolonifera (MAXIM.) KOMAR. (spike) ; 10,A. stelleriana BESS. (spike)] on bile flow, and biliary secretion of bile acids, cholesterol and phospholipids were examined in Wistar rats. Most of these extracts increased bile flow in 30 min after administration, and 1 (leaf) did after 30 min. The increased bile flow in 2 (spike), 3 (spike), 5 (spike), 6 (spike, leaf) and 7 (spike) gradually decreased thereafter, but that in 1 (leaf), 3 (leaf), 4 (spike, leaf), 5 (leaf), 8 (spike) and 9 (spike) remained at higher levels even in 120 or 150 min. Biliary secretion of bile acids, cholesterol and phospholipids decreased after administration of most of these extracts. These changes were not related to those in the bile flow.
社団法人日本薬学会の論文
1984-04-25