508 蠕動運動型マイクロポンプ内流れにおける赤血球挙動に関する数値解析(OS6.各種スケールにおける熱流動現象(2),オーガナイズドセッション)

概要

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A peristaltic pump, in which the channel walls periodically fluctuate in the form of a traveling wave, is believed to be an effective technique for micro miniature-sized devices due to its compactness, low fabrication cost and high applicability to various biological fluids. To apply this pump to medical fields, it is important to evaluate the cell behavior in the channel as well as the heat and mass transfer characteristics. In the present paper, numerical simulation using Immersed boundary method is conducted to study the characteristics of deformable red blood cells (RBC) in a channel of the peristaltic micro pump. The results showed that depending on the initial locations of the RBCs in the channel, some of the RBCs were convected into the contraction part of the channel. Most of the RBCs, however, reached around the center of the flow circulation formed in the channel under the condition of large peristaltic amplitude. This indicates the possibility of cell trapping or RBC aggregation at the center of the circulation.
一般社団法人日本機械学会の論文
2008-11-01