J0204-2-2 間葉系幹細胞を用いた修復軟骨の力学特性([J0204-2]バイオトライボロジー(2))

概要

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We have been developing a method of cartilage repair by means of a stem cell-based tissue engineered construct (TEC). The present study was performed to determine the coefficient of friction of cartilage-like tissue repaired with TEC. Amass of TEC was implanted into a cylindrically-shaped chondro defect created on the bearing surface of porcine femoral cartilage. Immediately and 60s after the application of compressive force, the coefficient of friction of the TEC-treated tissue was slightly decreased with the increase of load. Although, the coefficient of friction was significantly higher in the TEC-untreated tissue than in the normal cartilage immediately after the application of compressive load, no significant difference was observed as regard with coefficient of friction between the TEC-treated tissue and normal cartilage in all the conditions.
一般社団法人日本機械学会の論文
2010-09-04