J0203-1-1 咬筋における痛みと浮腫性変化に関する研究([J0203-1]ドラッグデリバリーシステム:技術開発と医療応用(1))

概要

論文の詳細を見る
To clarify the relationship between masseter muscle pain and its edematous changes, we investigated whether increased in thickness and plasma extravasation may occur in the rat masseter muscle as a result of capsaicin injection. In anaesthetized rat, capsaicin solution was injected into a masseter muscle on the one side, and vehicle into one on the other side. The thickness of the masseter muscle was measured by means of high-frequency ultrasound. Plasma extravasation was determined by means of the Evans blue dye method. As results, capsaicin injection into the masseter muscle induced thickening and plasma extravasation in the masseter muscle, and combination with local anaestesia counteracted the dye extravasation, indicating neurogenic inflammation change in rat masseter muscle.
2010-09-04