マイクロリットル血液粘性率の高速センシング法の開発(熱工学,内燃機関,動力など)

概要

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In the medical field, blood viscosity is known to be correlated with several diseases such as cardiac infarction and brain infarction. The blood viscosity may contribute to detection of diseases at an early stage and may give an indication of health state. There are several methods for measuring blood viscosity such as rotational viscometers and failing ball viscometers, but they need several milliliter sample volume and take several tens of seconds or several minutes to measure. So, we have developed a new viscometer which can measure viscosity within 1ms and with micro-liter sample volume. In the present study, we have developed a new viscometer by the laser-induced capillary wave using YAG laser. In this paper, first, we have measured viscosities of Newtonian liquids with 90μl sample volume and showed good agreement within ±10% from the reference values in the range from 10^<-1> to 10^1mPa・s. Then, we have measured healthy human blood with 90μl sample volume and compared to the reference values. The measured results of blood viscosity and surface tension were 4.5mPa・s and 54mN/m, respectively. The results were in good agreement with the reference with the estimated shear rate by the present method in the range of 10^2 to 10^3s^<-1>.
2010-08-25