抗MuSK抗体と抗アセチルコリン受容体抗体が陰性の重症筋無力症患者に関する電気生理検査の経験(神経内科学教室岩田誠教授退任記念特別号)

概要

論文の詳細を見る
We encountered an acetylcholine receptor (AChR) and muscle-specific tyrosine kinase (MuSK) antibody-negative myasthenia gravis (MG) patient with unique semiological and electrophysiological features. MG patients are divided into those with positive and negative anti-AChR antibody. It is occasionally difficult to diagnose as MG in patients with negative anti-AChR antibody. Because in our patient both anti-AChR and MuSK antibodies were negative, we had great difficulty in making definite diagnosis of MG. However, we were able to diagnose our patient as MG using combined edrophonium test and electrophysiological study. This combination may have a possibility to be applied in similar cases like ours. In addition, it was suggested from unique semiological and electrophysiological features that our patient had different pathogenesis from usual MG patients.
東京女子医科大学の論文
2008-02-25