2210 線維モデルを用いたブタ大動脈の引張変形挙動の記述 : 膠原線維の非線形特性の組込(OS22.計算バイオメカニクス(2),ポスターセッションP-3)

概要

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We formulate a mathematical model to describe the stress-strain relationship of the porcine thoracic aorta under uniaxial tensile loadings. We assume that the vascular wall consists of elastic fibers and collagen fibers, both orienting in three rectangular directions, and a fluid phase which has static pressure. It is also assumed that the distribution of the natural length of these fibers is expressed by a Gaussian function and that the elastic fibers show a linear stress-strain relationship while the collagen fibers show a nonlinear one under tension and no resistance under compression. The model is applied to simulate the stress-strain relationship of the aortic specimens with and without freezing and thawing. The numerical simulation results describe a hardening of the aorta by shortening the natural length of collagen fibers, which may reflect the micro-structural change in the collagen fiber networks.
社団法人日本機械学会の論文
2007-11-25