710 基質伸展下の培養血管内皮細胞に対する共焦点レーザ走査型顕微鏡を用いた輪郭形状測定(S07-1 マイクロ・ナノバイオメカニクス(1),S07 マイクロ・ナノバイオメカニクス)

概要

論文の詳細を見る
We measured the contours of cultured endothelial cells on a silicone substrate in unstretched and stretched states. Cells were scanned by confocal laser scanning microscopy. The interval of each image was 0.25μm in the vertical direction. The outline of each horizontal cross section of the cell was identified using a threshold of the fluorescence intensity. The error in the position of the outlines caused by the fading intensity of fluorescence was <1μm except the top region of the cell. For stretched cells, the difference in the position of the outlines between the results from the measurement and those from the finite element analysis was also <1μm except the top region. This indicates that a neo-Hookean material model describes the three-dimensional deformation under substrate stretching well.
社団法人日本機械学会の論文
2006-09-15