1452 血管収縮剤に対する活性化の筋長依存性を考慮した血管壁の力学的挙動のモデル化

概要

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Constitutive equations are proposed to describe the mechanical behavior of blood vessels in active state taking account of length dependency of the relationship between active stress development and muscle length under any concentration level of vessel contraction agent such as norepinephrine. The finite element model of the blood vessel consists of nine layers of passive elements and active elements. The passive element is modeled as an incompressible isotropic hyperelastic material. The total stress in the active element is modeled as an incompressible isotropic hyperelastic material. The total stress in the active element is expressed as the sum of the passive stress and active stress. The active stress develops in the circumferential direction of the blood vessel. A comparison of results from the finite element analysis with the experimental result of canine renal artery in the literature shows that the length dependency of activation plays an important role in the pressure-diameter relationship under activation.
一般社団法人日本機械学会の論文
2000-07-31