P-528 Biosynthetic Study of Antitumor Antibiotic Echinomycin : Formation of Quinoxaline Ring and Enzymatic Macrocyclization
スポンサーリンク
概要
- 論文の詳細を見る
- 天然有機化合物討論会の論文
- 2006-07-23
著者
-
WATANABE Kenji
Department of Kampo Medicine, Keio University, School of Medicine
-
Oikawa Hideaki
Div. Of Chemistry Graduate School Of Sci. Hokkaido Univ.
-
Oikawa Hideaki
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
-
OGURI Hiroki
Division of Chemistry, Graduate School of Science, Hokkaido University
-
Koketsu Kento
Division of Chemistry, Graduate School of Sciences, Hokkaido University
-
Watanabe Kenji
Department Of Gastroenterology Osaka City University Graduate School Of Medicine
-
Oguri Hiroki
Division Of Chemistry Graduate School Of Science Hokkaido University
-
Watanabe Kenji
Department Of Gastroenterology Graduate School Of Medicine Osaka City University
-
Watanabe Kenji
Department Of Anatomy Fukui Medical School
-
Watanabe Kenji
Division Of Chemistry Graduate School Of Science Hokkaido University
-
Watanabe Kenji
Department Of Agricultural Chemistry College Of Agriculture And Veterinary Medicine Nihon University
-
Watanabe Kenji
School Of Pharmaceutical Sciences University Of Shizuoka
関連論文
- Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms
- An Herbal Medicine Orengedokuto Prevents Indomethacin-Induced Enteropathy(Pharmacology)
- ADVANTAGES OF TRIPLE THERAPY WITH MIZORIBINE, CYCLOSPORINE AND PREDNISOLONE OVER OTHER TYPES OF TRIPLE AND/OR DOUBLE THERAPY INCLUDING CYCLOSPORINE FOR RENAL TRANSPLANTATION
- HRP intracellular staining using the monitored pressure injection combined with PAP immunohistochemistry
- Simple method of detection of the strains of fluorescent Pseudomonas spp. producing antibiotics, pyrrolnitrin and phloroglucinol
- Bioorganic Studies Utilizing Rationally Designed Synthetic Molecules : Absolute Configuration of Ciguatoxin and Development of Immunoassay Systems
- Reduction of 15-hydroxyprostaglandin dehydrogenase expression is an independent predictor of poor survival associated with enhanced cell proliferation in gastric adenocarcinoma
- Prevalence of mid-gastrointestinal bleeding in patients with acute overt gastrointestinal bleeding : multi-center experience with 1,044 consecutive patients
- A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding
- Phenotypic change and accumulation of smooth muscle cells in strictures in Crohn's disease : relevance to local angiotensin II system
- Transient activation of LHRH neuron system of the Japanese quail by photic stimuli of long days
- Wireless capsule endoscopy in pediatric patients : the first series from Japan
- Cloning and Heterologous Expression of a β-Fructofuranosidase Gene from Arthrobacter globiformis IFO 3062, and Site-Directed Mutagenesis of the Essential Aspartic Acid and Glutamic Acid of the Active Site (ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHN
- Cloning and Heterologous Expression of a Glucodextranase Gene from Arthrobacter globiformis I42, and Experimental Evidence for the Catalytic Diad of the Recombinant Enzyme(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Cloning of a Gene Cluster Responsible for the Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α
- Localization of Somatostatin Immunoreactive Cells in the Human Stomach and Pancreas
- DIFFERENT ONTOGENESIS OF α-ENDORPHIN POSITIVE CELLS IN THE ANTERIOR AND THE INTERMEDIATE LOBES OF RAT HYPOPHYSIS
- Correlative Ontogenic Development of Catecholaminergic Terminals and LHRH Terminals in the Rat Median Eminence
- ANTIFUNGAL ISOFLAVONE LUTEONE AND ITS METHYL ETHERS
- EXPRESSION OF BRUNO LIKE GENE IN STEM CELLS OF THE PLANARIAN DUGESIA JAPONICA(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- Planarian Cytochrome b_ : Conservation of a Six Transmembrane Structure and Localization along the Central and Peripheral Nervous System^1
- Diterpene Cyclases Responsible for the Biosynthesis of Phytoalexins, Momilactones A, B, and Oryzalexins A-F in Rice
- Potent Inhibition of Macrophomate Synthase by Reaction Intermediate Analogs
- Macrophomate Synthase: Characterization, Sequence, and Expression in Escherichia coli of the Novel Enzyme Catalyzing Unusual Multistep Transformation of 2-Pyrones to Benzoates^1
- The production of interferon-γ-inducible protein 10 by granulocytes and monocytes is associated with ulcerative colitis disease activity
- Effect of Soybean Saponin on Trypsin-Inhibiting Activity of Bowman-Birk Inhibitor
- Novel Statistical Classification Model of Type 2 Diabetes Mellitus Patients for Tailormade Prevention Using Data Mining Algorithm
- THE ROLES OF Xwnt8, FGF, VegT, Xbra IN FORMATION OF POSTERIOR STRUCTURES IN XENOPUS EMBRYOS(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- Characterization of a Rice Gene Family Encoding Type-A Diterpene Cyclases
- Enzymatic Conversion of Pheophorbide a to the Precursor of Pyropheophorbide a in Leaves of Chenopodium album
- Characterization of intracellular free Ca2+ movements in neural progenitor cells derived from ES cells transfected with MASH 1 transcription factor gene
- PRIMARY MALIGNANT LYMPHOMA OF THE PENIS : A CASE REPORT
- POTENTIAL OF AUTOFLUORESCENCE COLONOSCOPY FOR PATIENTS WITH ULCERATIVE COLITIS
- Crohn's disease complicated by adult-onset Still's disease
- NMR Determination of the Absolute Configuration of a Macrophomate Synthase Inhibitor by Using an Axial Chiral Reagent(Organic Chemistry)
- Synthesis of 2,2'-Anhydro-1-(3'-deoxy-3'-bromo-β-D-arabinofuranosyl)thymine and Its Derivatives from 5'-O-Trityl-2',3'-thymidinene
- Intracranial Extension of an Orbital Pseudotumor Accompanied by Internal Carotid Artery Occlusion : Case Report
- Substrate Diversity of Macrophomate Synthase Catalyzing an Unusual Multistep Transformation from 2-Pyrones to Benzoates
- Total Synthesis of (±) -syn-Copalol(Organic Chemistry)
- Total Synthesis of (+)-Albicanol and (+)-Albicanyl Acetate
- Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics
- Phosphoenolyruvate Carboxylase of an Ammonia-Oxidizing Chemoautotrophic Bacterium, Nitrosomonas europaea ATCC 25978
- Identification of Diterpene. Biosynthetic Gene Clusters and Functional Analysis of Labdane-Related Diterpene Cyclases in Phomopsis amygdali
- Purification and N-Terminal Amino Acid Sequence of Solanapyrone Synthase, A Natural Diels-Alderase from Alternaria solani
- Identification of a Gene Cluster of Polyether Antibiotic Lasalocid from Streptomyces lasaliensis
- Enzymatic Synthesis of Molecular Skeletons of Complex Antitumor Antibiotics with Non-ribosomal Peptide Synthetases
- Relative and Absolute Configuration of Antitumor Agent SW-163D
- P-556 Biosynthetic Study of Polyether Antibiotic Lasalocid
- P-528 Biosynthetic Study of Antitumor Antibiotic Echinomycin : Formation of Quinoxaline Ring and Enzymatic Macrocyclization
- Identification of asymmetrically localized transcripts along the animal-vegetal axis of the Xenopus egg
- Differential gene expression between the embryonic tail bud and regenerating larval tail in Xenopus laevis
- Hydrogen in Iron : Its Enhanced Dissolution under Pressure and Stabilization of the γ Phase
- PLANARIAN VASA-RELATED GENES EXPRESSED IN THE STEM CELLS(Developmental Biology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
- Involvement of the Diels-Alderases in the Biosynthesis of Natural Products
- Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α: Heterologous Expression of Four Biosynthetic Genes in Aspergillus oryzae
- Perturbation of Notch/Suppressor of Hairless pathway disturbs migration of primordial germ cells in Xenopus embryo
- Studies on the Later Stage of the Biosynthesis of Pleuromutilin
- The Relative and Absolute Configuration of PF1140
- Biosynthetic Study of FR-900848: Origin of the Aminodeoxynucleoside Part
- P-264 BIOSYNTHETIC STUDY OF FR-900848
- De novo development and self-replenishment of B cells
- Spinal cord is required for proper regeneration of the tail in Xenopus tadpoles
- Combined Studies of πN and NN Scattering and Electromagnetic Form Factor of Nucleon Based on the ππ Dynamics
- Cigarette Smoking and its Association with Overlapping Gastroesophageal Reflux Disease, Functional Dyspepsia, or Irritable Bowel Syndrome
- Target biopsy or step biopsy? Optimal surveillance for ulcerative colitis : a Japanese nationwide randomized controlled trial
- Role of Th-2 cytokines in the development of Barrett's esophagus in rats
- On the Electromagnetic Interactions in the B and D Mesons and Their Structure : Particles and Fields
- Exploring the Biosynthesis of Natural Products and Their Inherent Suitability for the Rational Design of Desirable Compounds through Genetic Engineering
- Novel Statistical Classification Model of Type 2 Diabetes Mellitus Patients for Tailormade Prevention Using Data Mining Algorithm
- Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α : Heterologous Expression of Four Biosynthetic Genes in Aspergillus oryzae
- Calorimetric Studies of the Behavior of Hydrogen in Vanadium and Vanadium Alloys
- A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases
- Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells
- Simple method of detection of the strains of fluorescent Pseudomonas spp. producing antibiotics, pyrrolnitrin and phloroglucinol
- Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics
- The Usefulness of Double-balloon Enteroscopy in Gastrointestinal Stromal Tumors of the Small Bowel with Obscure Gastrointestinal Bleeding
- Overexpressing transcriptional regulator in Chaetomium globosum activates a silent biosynthetic pathway : evaluation of shanorellin biosynthesis
- Clinical Classification of Subgroups According to the Rome III Criteria Cannot be Used to Distinguish the Associated Respective Pathophysiology in Japanese Patients with Functional Dyspepsia
- Precise Endoscopic and Pathologic Features in a Crohn's Disease Case with Two Fistula-associated Small Bowel Adenocarcinomas Complicated by an Anal Canal Adenocarcinoma
- Partition of Soybean Saponins between Butanol and Water.
- Analysis of localization and reorganization of germ plasm in Xenopus transgenic line with fluorescence-labeled mitochondria
- Trapping of hydrogen by solute atoms in Nb-Mo alloys as observed by the channelling method.
- Temperature-induced Structural Changes in Chicken Egg White Ovomucoid
- Oxidation of 2,4-alkadienoic esters with selenium dioxide. A new synthesis of furans and selenophenes.
- Antigenicity of Chicken Ovomucoid Domains I and III
- Secondary Structure Prediction of Chicken Egg White Ovomucoid
- Alteration of Ovalbumin Immunogenic Activity by Glycosylation through Maillard Reaction
- High prevalence of hepatitis C virus infection in Airin district, Osaka, Japan : A hospital-based study of 1162 patients
- Planarian Cytochrome b561: Conservation of a Six Transmembrane Structure and Localization along the Central and Peripheral Nervous System.