Biosynthetic Study of FR-900848: Origin of the Aminodeoxynucleoside Part
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概要
- 論文の詳細を見る
Biosynthetic studies of the antifungal agent, FR-900848, were undertaken by feeding experiments with D-[U-13C6]glucose, L-[4-13C]aspartate, [5,5-2H2]dihydrouridine and [5,5-2H2]dihydrouracil. The 5´´-amino-5´´-deoxy-5´,6´-dihydrouridine moiety was derived from ribose and aspartate. Based on the feeding experiments, a detailed biosynthetic pathway producing the aminodeoxydihydrouridine moiety of FR-900848 was proposed.
- 日本抗生物質学術協議会 (Japan Antibiotics Research Association)の論文
- 2006-09-25
著者
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Oikawa Hideaki
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Tokiwano Tetsuo
Division Of Chemistry Graduate School Of Science Hokkaido University
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Watanabe Hiroaki
Division Of Chemistry Graduate School Of Science Hokkaido University
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