Histometrical Study of Age Changes of the Arteries in Autopsied Submandibular Glands, and Relation with Age Changes of the Glands
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概要
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We studied histometrically the degeneration with aging of the submandibular glands removed from 103 autopsied cadavers (0〜102 years old). To evaluate arteriosclerosis of the medium- and small-sized arteries and the arterioles in the glands, we determined the stenotic index (SI). We assessed the correlations between SI and degeneration in the glands, age, general physical conditions and underlying diseases. SI of the medium- and small-sized arteries and the arterioles correlated with age (p < 0.001). Whereas, the medium- and small-sized arteries had intimal fibro-elastosis, the arterioles had hyaline arteriosclerosis in young cases and, in addition, intimal fibro-elastosis in elderly cases. As for degeneration, SI correlated with the grade of fatty infiltration and fibrosis but not with lymphoplasmacytic cell infiltration. The findings suggest that arteriosclerosis of the arteries in the glands is one of the causes of atrophy of the glands. SI correlated strongly with the atherosclerotic grade of the aorta and moderately with the atherosclerotic grade of the coronary artery. SI correlated weakly with heart weight/body weight ratio but not with BMI.
- 特定非営利活動法人日本臨床口腔病理学会の論文
- 2003-12-25
著者
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Ogawa Takafumi
Department Of Chemical Science And Engineering Graduate School Of Engineering Kobe University:instit
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Tanaka Michio
Department Of Pathology Tokyo Metropolitan Hiroo Generai Hospital
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Tanaka Michio
Department Of Pathology Tokyo Metropolitan Hiroo General Hospital
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Takagi Minoru
Molecular Pathology Department Of Oral Restitution Division Of Oral Health Sciences Graduate School
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Ishikawa Ayataka
Molecular Pathology, Graduate School of Tokyo Medical and Dental University
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Ishikawa Ayataka
Molecular Pathology Graduate School Of Tokyo Medical And Dental University:department Of Pathology T
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Tanaka Michio
Department Of Endoscopy Toyama Medical And Pharmaceutical University
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TANAKA Michio
Department of Clinical Laboratory, Tokyo Metropolitan Hiroo General Hospital
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