Different Histogenesis of Experimental Odontogenic Cysts by the Renal Subcapsular Transplantation of Tooth Germs of Mice

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The tooth germs of first mandibular molars of 17.5-day-old C3H mouse enbryos were transplanted into the renal subcapsular spaces of 3-month-old syngenic male mice.Grafts were harvested at timed sequences from 1, 2, 3, 4 weeks and 2, 3, 4, 5 months, and were examined histopathologically by total serial sections.Of32 cases of grafts, keratocyst-like lesions were formed in 13 cases, and dentigerous cyst-like lesions were formed in 7 cases.None of the cases developed two cysts at the same time.In the keratocyst-like lesions the cavity developed from the enamel epithelium in the early stage after transplantation, and in the dentigerous cyst-like lesion the cavity developed by cystic degeneration of stellate reticular layer of enamel organ in the late stage after transplantation.The present experiment revealed that keratocyst-like lesions and dentigerous cyst-like lesions developed through different histogeneses.
特定非営利活動法人日本臨床口腔病理学会の論文
2000-12-20