633 無負荷状態における弾性動脈壁内弾性板の蛇行に与える微視的残留応力の影響(G02-5 血流(2),G02 バイオエンジニアリング)

概要

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Elastic laminas (ELs) in unloaded elastic arteries are usually corrugated. In this study, we examined whether the corrugation could be caused by the compressive residual stress residing in the ELs. Corrugation was evaluated by a waviness, the length along corrugation divided by the length along global curvature of ELs. Waviness in ring-like specimens decreased from 1.32 to 1.27 in the internal elastic lamina (IEL) upon radial cutting to release macroscopic residual stress. After the specimens were frozen and thawed to disrupt smooth muscle cells bearing tensile stress, waviness decreased further to 1.24 in the IEL, corresponding to the release of microscopic residual stress. Waviness decreased again when ELs were dissected from surrounding tissues, and decreased further when the surrounding tissues were removed completely with collagenase treatment. These results may indicate that ELs were compressed by the surrounding tissues including smooth muscle cells to form their corrugation.
一般社団法人日本機械学会の論文
2006-09-15