Deep vein thrombosis and pulmonary thromboembolism in a patient with eosinophilia and obesity

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概要

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• A 46-year-old female patient with deep vein thrombosis (DVT) and pulmonary embolism complicated with disseminated intravascular coagulation was admitted to our hospital. She was treated with urokinase and repeated plasma exchange and with the administration of low-molecular-weight heparin coupled with a high dose of glucocorticoid after inferior vena cava (IVC) filter placement. As the etiology of DVT, blood tests showed no evidence of antiphospholipid syndrome or protein S/C deficiency except for hypereosinophilia and obesity with a high body mass index (34 kg/m2). Activated protein C (APC) resistance was not detected. Eosinophilia coupled with remarkable obesity was considered to be the trigger of DVT in this patient. After intensive therapy along with strict anti-coagulant agents, effective reduction of thrombosis in both the IVC and pulmonary arteries was observed along with improvement of the coagulation system.

• 長崎大学の論文

著者

• Arima Kazuhiko

  Department Of Clinical Chemistry And Laboratory Medicine

• ORIGUCHI Tomoki

  Nagasaki University School of Health Sciences

• NAKAMURA HIDEKI

  First Department of Internal Medicine, Nagasaki University School of Medicine

• Yamachika Shiro

  Department of Cardiovascular Surgery, Graduate School of Medicine, Nagasaki University

• Origuchi Tomoki

  Nagasaki University School Of Health Scinece

• Kamihira Shimeru.

  Central Diagnostic Laboratory Nagasaki University Hospital

• Tsuchihashi Yoshiko

  Department of Internal Medicine, Institute of Tropical Medicine, Nagasaki University

• Nakamura Hideki

  First Department Of Internal Medicine Nagasaki University Hospital Of Medicine And Dentistry Graduat

• Tsuchihashi Yoshiko

  Department Of Internal Medicine Institute Of Tropical Medicine Nagasaki University

• Yamachika Shiro

  Department Of Cardiovascular Surgery Nagasaki University School Of Medicine

• Yamachika Shiro

  Department Of Cardiovascular Surgery Graduate School Of Medicine Nagasaki University

• Nakamura Hideki

  First Department Of Internal Medicine Graduate School Of Biomedical Sciences Nagasaki University

• Tsuchihashi Yoshiko

  Department Of Clinical Medicine Institute Of Tropical Medicine Nagasaki University

• Iwamoto Naoki

  Department Of Applied Biological Chemistry Graduate School Of Agriculture Kinki University

• Yamachika Shiro

  Department Of Cardiology Inoue Hospital

• Aramaki Toshiyuki

  Nagasaki University School of Health Scinece

• Nakajima Hideki

  Central Diagnostic Laboratory, Nagasaki University Hospital

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