Infliximab is Effective for Takayasu Arteritis Refractory to Glucocorticoid and Methotrexate

スポンサーリンク

概要

• 論文の詳細を見る

• We have experienced a Takayasu arteritis (TA) patient, successfully treated with infliximab, who did not respond well to conventional therapy with glucocosteroid and methotrexate. Takayasu arteritis had developed in a 24yearold woman (March 2003) who had been treated with glucocorticoid including methylprednisolone pulse therapy and methotrexate; however, she relapsed during the tapering of the dosage of oral prednisolone. Nineteen months after the first administration of glucocorticoid, 3 mg/kg of infliximab was introduced to the patient. The therapeutic efficacy of infliximab was markedly demonstrated; the patient's Creactive protein (CRP) value returned to almost normal range with subsequent tapering of the dosage of oral prednisolone in the absence of further relapse. This is the first case presentation of TA in Japan successfully treated with infliximab.

• 日本内科学会の論文

著者

• Ida Hiroaki

  First Department Of Internal Medicine Graduate School Of Biochemical Sciences Nagasaki University

• Izumi Yasumori

  First Department Of Internal Medicine Nagasaki University Hospital Of Medicine And Dentistry Graduat

• Tanaka Fumiko

  First Department Of Internal Medicine Nagasaki University School Of Medicine

• Arima Kazuhiko

  First Department Of Internal Medicine Nagasaki University Hospital Of Medicine And Dentistry Graduat

• Kawakami Atsushi

  First Department Of Internal Medicine Nagasaki University Hospital Of Medicine And Dentistry Graduat

• Aratake Kouichiro

  First Department Of Internal Medicine Graduate School Of Biochemical Sciences Nagasaki University

• Huang Mingguo

  First Department Of Internal Medicine Nagasaki University Hospital Of Medicine And Dentistry Graduat

• Iwanaga Nozomi

  First Department Of Internal Medicine Graduate School Of Biochemical Sciences Nagasaki University

• Eguchi Katsumi

  First Department Of Internal Medicine Graduate School Of Biochemical Sciences Nagasaki University

• Kamachi Makoto

  First Department Of Internal Medicine Nagasaki University Hospital Of Medicine And Dentistry Graduat

• Nakamura Hideki

  First Department Of Internal Medicine Graduate School Of Biomedical Sciences Nagasaki University

• Origuchi Tomoki

  Nagasaki University of Health Science, Nagasaki University

• Tamai Mami

  First Department of Internal Medicine Atomic Bomb Disease Institute, Nagasaki University School of Medicine

• Tanaka Fumiko

  First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University

• Huang Mingguo

  First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University

• Izumi Yasumori

  First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University

• Kamachi Makoto

  First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University

関連論文

• Enhanced effect of high-dose leukocytapheresis using a large filter in rheumatoid arthritis
• Sarcoidosis Accompanied by Systemic Lupus Erythematosus and Autoimmune Hepatitis
• Adult Still's disease associated with cytomegalovirus infection
• Prediction of DAS28-ESR remission at 6 months by baseline variables in patients with rheumatoid arthritis treated with etanercept in Japanese population
• Membraneous Glomerulonephritis and Non-Hodgkin's Lymphoma in a Patient with Primary Sjﾃｶgren's Syndrome
• Autoimmune hepatitis in a patient with systemic lupus erythematosus : a case report
• A case of Sjogren's syndrome presenting as hypokalemic myopathy due to distal renal tubular acidosis
• Catastrophic transverse myelitis in a patient with systemic lupus erythematosus
• Association of subacute cutaneous lupus erythematosus in a rheumatoid arthritis patient with Sjogren's syndrome
• A significantly impaired natural killer cell activity due to a low activity on a per-cell basis in rheumatoid arthritis
• Twenty-four-week follow-up examination of a leukocytapheresis therapy in rheumatoid arthritis
• Characterization of anticytoplasmic antibodies in patients with systemic autoimmune diseases
• A case of amyloidosis secondary to rheumatoid arthritis complicated with Graves' ophthalmopathy
• Atypical mycobacteriosis in two patients with rheumatoid arthritis
• Successful Combined Therapy of Cyclophosphamide and Cyclosporine for Acute Exacerbated Interstitial Pneumonia Associated with Dermatomyositis
• Nonalcoholic Steatohepatitis with Improved Hepatic Fibrosis after Weight Reduction
• Clinical Features of Fulminant Hepatitis in Nagasaki Prefecture, Japan
• Spontaneous loss of hepatitis B surface antigen in chronic carriers, based on a long-term follow-up study in Goto Islands, Japan
• Deep vein thrombosis and pulmonary thromboembolism in a patient with eosinophilia and obesity
• Thyrotropin Secreting Pituitary Adenoma Effectively Treated with Octreotide
• Lens culinaris agglutinin-reactive α-fetoprotein and protein induced by vitamin K absence II are potential indicators of a poor prognosis : a histopathological study of surgically resected hepatocellular carcinoma
• Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in Japanese
• Successful plasmapheresis in alveolar hemorrhage associated with systemic lupus erythematosus
• Tyrphostin AG 1478 Accelerates Hydrogen Peroxide-Induced Apoptosis in A431 Cells
• A case of periodic-fever-syndrome-like disorder with lipodystrophy, myositis, and autoimmune abnormalities
• Transient Appearance of Lactate Dehydrogenase (LDH)-linked Immunoglobulin and Thyroid Dysfunction at the Postpartum Period
• Hereditary Periodic Fever Syndromes in Japan
• Update on the Japanese guidelines for the use of infliximab and etanercept in rheumatoid arthritis
• Guidelines for the proper use of etanercept in Japan
• Increased mRNA Expression of Th1-Cytokine Signaling Molecules in Patients with HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis
• Multicentric reticulohistiocytosis associated with ovarian cancer
• Role of HTLV-I infection in the pathogenesis of Sjogren's syndrome and rheumatoid arthritis
• Anti-Thyroid Drug-Induced ANCA-Associated Vasculitis: A Case Report and Review of the Literature
• Cutaneous vasculitis induced by TNF inhibitors : a report of three cases
• Switching to the anti-interleukin-6 receptor antibody tocilizumab in rheumatoid arthritis patients refractory to antitumor necrosis factor biologics
• Prediction of DAS28-CRP remission in patients with rheumatoid arthritis treated with tacrolimus at 6 months by baseline variables
• Vasculo-Behcet's syndrome with widespread arterial involvement
• Successful treatment of chronic lupus myocarditis with prednisolone and mizoribine
• Contribution of an adenine to guanine single nucleotide polymorphism of the matrix metalloproteinase-13 (MMP-13) -77 promoter region to the production of anticyclic citrullinated peptide antibodies in patients with HLA-DRB1^*shared epitope-negative rheuma
• Reduction in serum levels of substance P in patients with rheumatoid arthritis by etanercept, a tumor necrosis factor inhibitor
• Putative IgG4-related pituitary disease with hypopituitarism and/or diabetes insipidus accompanied with elevated serum levels of IgG4
• Emergence of anti-islet autoantibodies in Japanese patients with type 1 diabetes
• First Japanese Patient Treated with Parathyroid Hormone Peptide Immunization for Refractory Hypercalcemia Caused by Metastatic Parathyroid Carcinoma
• In rheumatoid arthritis patients treated with tocilizumab, the rate of clinical disease activity index (CDAI) remission at 24 weeks is superior in those with higher titers of IgM-rheumatoid factor at baseline
• Disease activity score 28 may overestimate the remission induction of rheumatoid arthritis patients treated with tocilizumab : comparison with the remission by the clinical disease activity index
• Successful Treatment of a Patient with Primary Sjögren's Syndrome Complicated with Pericarditis during Pregnancy
• Blockade of IL-2 Receptor Suppresses HTLV-I and IFN-ﾎｳ Expression in Patients with HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis
• Delayed treatment with tumor necrosis factor inhibitors in incomplete responders to synthetic disease-modifying anti-rheumatic drugs shows and excellent effect in patients with very early rheumatoid arthritis with poor prognosis factors
• A patient with systemic lupus erythematosus who developed massive small intestinal hemorrhaging during treatment for chronic lupus peritonitis
• Treatment discontinuation in patients with very early rheumatoid arthritis in sustained simplified disease activity index remission after synthetic disease-modifying anti-rheumatic drug administration
• A case of Sjogren's syndrome presenting as trigeminal nerve palsy
• Thyroid papillary carcinoma with solid sclerosing change in IgG4-related sclerosing disease
• Type B Insulin Resistance Complicated with Systemic Lupus Erythematosus
• Non-specific Activities against Ruthenium Crosslinker as a New Cause of Assay Interference in an Electrochemilluminescent Immunoassay
• Examination of IgM Rheumatoid Factor (IgM-RF) and Anti-cyclic Citrullinated Peptide Antibody (Anti-CCP Ab) in Japanese Patients with Palindromic Rheumatism
• Infliximab is Effective for Takayasu Arteritis Refractory to Glucocorticoid and Methotrexate

もっと見る 閉じる

スポンサーリンク