Hyper-heterogeneity of the N-Terminus of Recombinant BSF-2/IL-6 Produced in CHO and NIH3T3 Cells(Microbiology & Fermentation Industry)
スポンサーリンク
概要
- 論文の詳細を見る
Recombinant human BSF-2 (B cell stimulatory factor 2/InterIeukin 6; IL-6) proteins were purified from CHO and NIH3T3 cell cultures and characterized. The lectin binding patterns suggested that the proteins have N-linked oligosaccharide(s) with tri-antennary structure of bisecting GlcNAc. Their N-termini were highly heterogeneous; at least five closely related N-termini were detercted. This N-terminal heterogeneity was not generated in the cell culture because no processing activity was found in the culture medium.
- 社団法人日本農芸化学会の論文
- 1990-10-23
著者
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Tonouchi Naoto
Central Research Laboratories Ajinomoto Co. Inc.
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MATSUI HIROSHI
Central Research Laboratories, Ajinomoto Co., Inc.,
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MIWA Kiyoshi
Central Research Laboratories, Ajinomoto Co., Inc.
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Miwa Kiyoshi
Central Research Laboratories Ajinomoto Co. Inc.
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MIYASAKA Yuko
Central Research Laboratories, Ajinomoto Co., Inc.
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Miyasaka Yuko
Central Research Laboratories Ajinomoto Co. Inc.
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Matsui Hiroshi
Central Research Laboratories Ajinomoto Co. Inc.
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