Synthesis of a Bicyclo[3.2.1]octane Analogue of Isocarbacyclin(Organic,Chemical)
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概要
- 論文の詳細を見る
A new isocarbacyclin analogue (1a), containing a bicyclo[3.2.1]octane ring system, has been synthesized by means of a regioselective rearrangement of the cyclopropyl carbinol (8) to the homoallyl bromide (9) with hydrobromic acid. Compound la showed very weak inhibitory activity against platelet aggregation.
- 公益社団法人日本薬学会の論文
- 1987-06-25
著者
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小島 孝一
Chemical Research Laboratories, Sankyo Co., Ltd.
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小山 和男
Chemical Research Laboratories Sankyo Co., Ltd.
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小島 孝一
Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.
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小山 和男
Faculty Of Pharmaceutical Sciences Chiba University
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