SYNTHESIS OF A HIGHLY POTENT ANALOGUE OF PROSTACYCLIN, (-)-5-METHYLENEISOCARBACYCLIN

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概要

• 論文の詳細を見る

• Synthesis of (-)-5-methyleneisocarbacyclin (1a) is described. The compound (1a) was found to be a platelet aggregation inhibitor as potent as prostacyclin.

• 公益社団法人日本薬学会の論文
• 1986-10-25

著者

• 小島 孝一

  Chemical Research Laboratories, Sankyo Co., Ltd.

• 雨宮 茂雄

  Chemical Research Laboratories Sankyo Co., Ltd.

• 小山 和男

  Chemical Research Laboratories Sankyo Co., Ltd.

• 斉藤 進一

  Chemical Research Laboratories Sankyo Co., Ltd.

• 小島 孝一

  Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.

• 斉藤 進一

  Chemical Research Laboratories Sankyo Co. Ltd.

• 雨宮 茂雄

  Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.

• 小山 和男

  Faculty Of Pharmaceutical Sciences Chiba University

関連論文

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• Total Synthesis of dl-8β-Methoxycarbonylestrone 3-Methyl Ether
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• A Stereoselective Synthesis of a Stable Prostacyclin Analogue : dl-3-Oxa-9(O)-methano-Δ^-prostaglandin I_1(Organic,Chemical)
• SYNTHESIS OF A HIGHLY POTENT ANALOGUE OF PROSTACYCLIN, (-)-5-METHYLENEISOCARBACYCLIN
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