Complete Response to Temozolomide Treatment in an Elderly Patient With Recurrent Primary Central Nervous System Lymphoma : Case Report
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概要
- 論文の詳細を見る
An 80-year-old woman presented with primary central nervous system (CNS) lymphoma manifesting as progressive disorientation and loss of activity. She received three cycles of high-dose methotrexate. The tumor shrank after two cycles and her mental status improved, but she suffered tumor recurrence. The second-line treatment consisted of four cycles of rituximab but the tumor enlarged. She was then treated with three cycles of temozolomide. Magnetic resonance imaging revealed no evidence of disease. Her mental status and performance status improved, and she suffered no toxicity. She is able to pursue her daily life without recurrence after 16 cycles of temozolomide. Temozolomide may be effective against relapsed primary CNS lymphoma without causing neurotoxicity in the elderly.
- 社団法人 日本脳神経外科学会の論文
- 2007-05-15
著者
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Nakamura Hideo
Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine
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KURATSU Jun-ichi
Department of Neurosurgery, Kumamoto University Medical School
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KUDO Mareina
Department of Neurosurgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University Grad
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MAKINO Keishi
Department of Neurosurgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University Grad
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Kuratsu Jun-ichi
Department Of Neurosurgery Faculty Of Medical And Pharmaceutical Sciences Kumamoto University Gradua
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Kudo Mareina
Department Of Neurosurgery Faculty Of Medical And Pharmaceutical Sciences Kumamoto University Gradua
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Makino Keishi
Department Of Neurosurgery Faculty Of Medical And Pharmaceutical Sciences Kumamoto University Gradua
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Kuratsu Jun-ichi
Department Of Neurosurgery Graduate School Of Medical Sciences Kumamoto University
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Kuratsu Jun-ichi
Department Of Neurosurgery Faculty Of Medical And Pharmaceutical Sciences Kumamoto University
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Kuratsu Jun-ichi
Department Of Neurosurgery Kumamoto University School Of Medicine
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TAKESHIMA Hideo
Department of Neurosurgery, Faculty of Medicine, Kagoshima University
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Kuratsu Jun-ichi
Department Of Neurosurgery Shimonoseki Kosei Hospital
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Takeshima Hideo
Department Of Neurosurgery Faculty Of Medical And Pharmaceutical Sciences Kumamoto University
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Nakamura Hideo
Department Of Cardiovascular Medicine Kyoto Prefectural University Of Medicine
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Nakamura Hideo
Department Of Neurosurgery Graduate School Of Medical Sciences Kumamoto University
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Nakamura Hideo
Department Of Cardiology Kyoto Prefectural Yosanoumi Hospital
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Kuratsu Jun-ichi
Department Of Neurosurgery Faculty Of Medical And Pharmaceutical Sciences Kumamoto University Gradua
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